Detalhes bibliográficos
| Ano de defesa: |
2013 |
| Autor(a) principal: |
Silva, Daniel D'oliveira |
| Orientador(a): |
Carvalhal, Gustavo Franco
 |
| Banca de defesa: |
Não Informado pela instituição |
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Pontifícia Universidade Católica do Rio Grande do Sul
|
| Programa de Pós-Graduação: |
Programa de Pós-Graduação em Medicina e Ciências da Saúde
|
| Departamento: |
Faculdade de Medicina
|
| País: |
BR
|
| Palavras-chave em Português: |
|
| Área do conhecimento CNPq: |
|
| Link de acesso: |
http://tede2.pucrs.br/tede2/handle/tede/1726
|
Resumo: |
Renal cell carcinomas (RCCs) are among most the most lethal malignant neoplasms. Despite the evolution in the development of new drugs and imaging studies, mortality rates have increased around the world. Currently, to establish risks of mortality in RCC patients are classified according to scales and nomograms that can‗t accurately predict clinical outcomes. The association between cancer and thromboembolic events is well known for a long time. A few years ago, researchers identified tissue factor as one of the proteins responsible for these phenomena and several studies have been conducted trying to correlate the expression of tissue factor with cancer. In 2009, a study conducted by our group described the important association between the immunohistochemical expression of tissue factor and mortality in patients with Wilms' tumours. The aim of the present study was to correlate the immunohistochemical expression tissue factor with prognostic factors and mortality in 58 patients surgically treated at Hospital São Lucas in the years 2004 to 2007, who had been followed for at least five years. |
