Estudo comparativo da necessidade de transfusão sangüínea em pacientes submetidos à esplenectomia por púrpura trombocitopênica imune, com e sem embolização pré-operatória da artéria esplênica

• Ano de defesa: 2007
• Autor(a) principal: Baú, Plínio Carlos
• Orientador(a): Garicochea, Bernardo
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul; Porto Alegre
• Palavras-chave em Português: MEDICINA; HEMATOLOGIA; SANGUE - TRANSFUSÃO; EMBOLIZAÇÃO; ESPLENECTOMIA; PERÍODO PÓS-OPERATÓRIO; PLAQUETAS
• Link de acesso: http://hdl.handle.net/10923/4376

Platelet and/or red blood cell transfusion is usually necessary immediately after the splenic artery ligature in patients with Immune Thrombocytopenic Purpura who are submitted to splenectomy. The purpose of this study is to test whether preoperative embolization of the splenic artery can reduce the need for transfusion of platelets and/or red blood cells. Twenty-seven consecutive patients submitted to splenectomy for purpura between October 1999 and March 2006 by the same surgical team were enrolled. The first 17 patients were not submitted to embolization and were compared to the next 10 patients in whom embolization was performed. The platelet count in the embolization group rose from an average of 7000 u/μl before the procedure to 75000 u/μl afterwards. There was no need for platelet and red blood cell transfusion in the group submitted to embolization compared to 11 patients (p=0. 001) with platelet transfusion and 8 patients (p=0. 01) with red blood cell transfusion in the group without preoperative embolization. We concluded that embolization of the splenic artery pre-splenectomy is a safe method to avoid blood transfusion in ITP patients.