Validade e reprodutibilidade do COPD assessment test (CAT) em pacientes com bronquiectasia n??o-fibrose c??stica

Detalhes bibliográficos
Ano de defesa: 2015
Autor(a) principal: Castro, Rejane Agnelo Silva de lattes
Orientador(a): Lanza, Fernanda de Cordoba
Banca de defesa: Lanza, Fernanda de Cordoba, Gazzotti, Mariana Rodrigues, Corso, Simone Dal
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Nove de Julho
Programa de Pós-Graduação: Programa de P??s-Gradua????o em Ci??ncias da Reabilita????o
Departamento: Sa??de
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://bibliotecatede.uninove.br/handle/tede/1817
Resumo: Introduction: Instruments to objectively assess the perception of symptoms in patients with BCQ are scarce. Patients with COPD and bronchiectasis (BCQ) share similar symptoms. Therefore, COPD Assesment Test (CAT), originally developed for COPD may be suitable for use in these patients. Objective: To validate and test the reproducibility of the CAT for non-cystic fibrosis (non???CF) bronchiectasis patients. Methods: Hundred patients (FEV1 52 ?? 25%; FVC 67 ?? 22%; 48 ?? 14 years; 42 males) underwent spirometry, cardiopulmonary exercise testing (peak workload and VO2), and shuttle walk test (ST). They answered the Saint George Respiratory Questionnaire (SGRQ) and the Medical Research Council (MRC) scale, and the CAT in two different days (CAT-1 and CAT-2). A pedometer recorded the No. of steps/day (NSD). Results: CAT showed a positive correlation with SGRQ domains (r = 0.74, p< 0.001) and MRC (r = 0.49, p< 0.001). A negative correlation was observed among CAT and lung function (FVC%: r= -0.33, p= 0.001; FEV1%: -0.28, p = 0.004), peak workload (r = -0.31, p = 0.001), VO2 (r = -0.44 p< 0.001), distance walked on ST (%, r= -0.46, p< 0.001), and NSD (r = -0.74, p< 0.001). There was an excellent reliability in the scores from CAT-1 and CAT-2 (21 ???13.25 ??? 26.75??? and (19 ???13 ??? 26.75???, respectively) with high intraclass correlation coefficient (ICC: 0.92 [95% CI: 0.83 ??? 0.96], p< 0.001). Conclusion: CAT is a valid instrument for measuring the impact of bronchiectasis in well-being and daily life of patients with BCT, and is a reproducible questionnaire.