Bypass intestinal restritivo parcial: cirurgia de Lazzarotto revisão das principais técnicas de cirurgia bariátrica e análise clínica retrospectiva

• Ano de defesa: 2020
• Autor(a) principal: Souza, José Lazzarotto de Melo e
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Positivo; Brasil; Pós-Graduação; Programa de Pós-Graduação em Biotecnologia Industrial; UP
• Palavras-chave em Português: Biotecnologia industrial; Obesidade; Cirurgia bariátrica; Derivação jejunoileal; CNPQ::CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
• Link de acesso: https://repositorio.cruzeirodosul.edu.br/handle/123456789/2296

Obesity is a public health issue around the world. When other therapies have not been successful in the obesity treatment, bariatric surgery should be used. The present study has aimed to present a brief review of the literature on the subject, with a description of the main techniques, including the intestinal bypass Lazzarotto surgery and to perform retrospective analysis of patients submitted to this technique. The retrospective analysis was performed on data collected from 100 patients over a 24-month period submitted to the Lazzarotto surgery technique between 2006-2018. The data were submitted to the Shapiro-Wilk, ANOVA and Tukey tests. The comparison between the means of the body mass index (BMI) was submitted to the t test. The comparison of frequencies was done using the chi-square test. The odds ratio, Pearson's correlation test and linear logistic regression were compared, always with p <0.05. The initial average BMI was statistically different from the BMI at 6, 12 and 24 months (p <0.0001). The levels of triglycerides, cholesterol, glucose, AST, ALT, and initial total proteins were statistically lower at 6, 12 and 24 months (p <0.0001). Albumin did not show a statistically significant variation over time (p> 0.05). Stool frequency was significantly higher between 0 and 6 months, 0 and 12 months, and 6 and 12 months (p <0.001). It was concluded that the Lazzarotto procedure increased stool frequency (average lower than 3/day), was efficient in reducing comorbidities and decreasing BMI. Such knowledge may arouse the interest of surgeons in this technique to develop more advanced and less invasive surgical techniques for the treatment of obesity.