Efeito tóxico de quatro antibióticos sobre três organismos aquáticos

• Ano de defesa: 2013
• Autor(a) principal: Dalke, Carlos Roberto
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Positivo; Brasil; Pós-Graduação; Programa de Pós-Graduação em Biotecnologia Industrial; UP
• Palavras-chave em Português: Testes de toxicidade; Antibióticos; Toxicologia ambiental; Organismos aquáticos; CNPQ::CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
• Link de acesso: https://repositorio.cruzeirodosul.edu.br/handle/123456789/2573

The presence of medicine residue in the aquatic environment is a fact these days. It is necessary to know what its effects are and what this presence can cause on organisms more deeply. The purpose of this work is to study the effects of the following antibiotics: metronidazole, nitrofurantoin, trimethoprim and sulfamethoxazole on bioindicators such as Vibrio fischeri, Daphnia magna and Desmodesmus subspicatus. The evaluation of the toxic effect of antibiotics on bioindicators such as Daphnia magna, Vibrio fischeri and Desmodesmus subspicatus have been based on tests concerning mobility, fluorescence and bioluminescence, respectively. The four antibiotics tested in isolation have showed toxic effect on those organisms evaluated. The sulfamethoxazole has caused higher toxic effect on Vibrio fischeri and on Desmodesmus subspicatus and metronidazole has caused effect on the mobility of Daphnia magna. Trimethoprim and sulfamethoxazole have showed similar effect to hormesis for concentrations ranging from 7.81 to 62.5 µgL-1. The mixture of antimicrobials has had an effect on the following organisms: D. magna, Vibrio fischeri and Desmodesmus subspicatus in lower concentrations in relation to when the antibiotics were evaluated individually. The organisms tested have suffered the effects of different magnitudes for each antibiotic tested in isolation and when mixed together