Detalhes bibliográficos
| Ano de defesa: |
2015 |
| Autor(a) principal: |
Fernández, Hugo Roberto |
| Orientador(a): |
Struchiner, Claudio José,
Vilela, Daniel Antunes Maciel |
| Banca de defesa: |
Não Informado pela instituição |
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Não Informado pela instituição
|
| Programa de Pós-Graduação: |
Não Informado pela instituição
|
| Departamento: |
Não Informado pela instituição
|
| País: |
Não Informado pela instituição
|
| Link de acesso: |
https://www.arca.fiocruz.br/handle/icict/40239
|
Resumo: |
The link between Diabetes and Tuberculosis has been recognized for long time. In recent decades acquired epidemiological importance in light of the expansion of the epidemic of type 2 diabetes mellitus in TB-endemic settings. The coexistence of diabetes and tuberculosis could have serious implications on TB control in many developing countries and be the next challenge for the global control of tuberculosis. In this context a better understanding of the interaction between the two diseases will allow better tools to address their control. Mathematical models are tools that have played a key role in strategies for TB control and the establishment of intermediate targets for intervention programs. This work presents a model, which includes the main components of the dynamics of tuberculosis and evaluates the dynamics for diabetes to change this behavior, worsening the situation of tuberculosis. A deterministic population-based model is proposed to analyze the impact of diabetes on the dynamics and treatment of Tuberculosis. The model calibrated with data estimated by WHO TB allowed projecting various scenarios for Argentina, generated from the evidence of interaction between the two conditions and intervention measures. The results are consistent with the international literature as evidence of a negative impact of the increase in diabetes in the situation of tuberculosis and its control. |
