Fatores associados à tuberculose em população de diabéticos : um estudo caso-controle

• Ano de defesa: 2016
• Autor(a) principal: Leal, Marcelle Lemos
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Espírito Santo; BR; Mestrado em Saúde Coletiva; Centro de Ciências da Saúde; UFES; Programa de Pós-Graduação em Saúde Coletiva
• Palavras-chave em Português: Tuberculosis; Case-control study; Epidemiology; Diabetes mellitus; Diabetes; Tuberculose; Estudos de casos e controles; Epidemiologia; Saúde Coletiva; 614
• Link de acesso: http://repositorio.ufes.br/handle/10/5574

Individually, diabetes mellitus (DM) and tuberculosis (TB) have an important impact on public health worldwide. There is evidence that people with DM have a three times higher risk of catching TB than the general population’s susceptibility to infections. This study investigates the factors associated to developing tuberculosis in patients with diabetes mellitus being treated at health units in Vitória/Espírito Santo. It is a case-control study, with the case group comprising diabetic patients treated at the 30 units in the municipality and notified on the National Disease Notification System (SINAN), with a diagnosis of tuberculosis during the period 2007 to 2013, and the control group comprising people with diabetes. Data was used from SINAN, the Health Information System at the Department of Health in Vitória and Central Municipal Laboratory. An interview held with a semi-structured script was applied to 45 cases and 92 controls, considering social, economic and demographic variables, lifestyle habits and clinical characteristics of diabetes. Bi-varied and multivaried analyses were performed by means of logistic regression with significant variables (p<0.05). The case group presents worse lifestyle habits compared with the control group, such as higher regular consumption of alcohol (p=0.008), compulsive consumption of alcohol (p<0.001), smokes more (p=0.051), in addition to worse biochemical parameters, such as fasting blood sugar (p<0.001) and higher glycosylated haemoglobin (p=0.027). Higher regular consumption of alcohol (OR 5.78; IC 1.726-19.359), previous contact with people with tuberculosis (OR 3.773; IC 1.161-12.258) and fasting blood sugar (OR 1.012; IC 1.001-1.024) were associated to tuberculosis in those with diabetes. As a result, this study reiterates the need for integration between the tuberculosis and diabetes mellitus control programmes for screening, confirming diagnosis and the joint handling of these diseases.