A distributed computation of Interpro Pfam, PROSITE and ProDom for protein annotation

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Ribeiro, Edward de Oliveira
Julkaisupäivä: 2005
Muut tekijät: Zerlotini, Gustavo G., Lopes, Irving R. M., Ribeiro, Victor B. R., Melo, Melo, Alba Cristina Magalhães Alves de, Walter, Maria Emília Machado Telles, Costa, Marcos Mota, BIOFOCO Network
Aineistotyyppi: Article
Kieli: eng
Lähde: Repositório Institucional da UnB
Download full: http://repositorio.unb.br/handle/10482/32103
Yhteenveto: Interpro is a widely used tool for protein annotation in genome sequencing projects, demanding a large amount of computation and representing a huge time-consuming step. We present a strategy to execute programs using databases Pfam, PROSITE and ProDom of Interpro in a distributed environment using a Java-based messaging system. We developed a two-layer scheduling architecture of the distributed infrastructure. Then, we made experiments and analyzed the results. Our distributed system gave much better results than Interpro Pfam, PROSITE and ProDom running in a centralized platform. This approach seems to be appropriate and promising for highly demanding computational tools used for biological applications.
Kuvaus
Yhteenveto:Interpro is a widely used tool for protein annotation in genome sequencing projects, demanding a large amount of computation and representing a huge time-consuming step. We present a strategy to execute programs using databases Pfam, PROSITE and ProDom of Interpro in a distributed environment using a Java-based messaging system. We developed a two-layer scheduling architecture of the distributed infrastructure. Then, we made experiments and analyzed the results. Our distributed system gave much better results than Interpro Pfam, PROSITE and ProDom running in a centralized platform. This approach seems to be appropriate and promising for highly demanding computational tools used for biological applications.