A distributed computation of Interpro Pfam, PROSITE and ProDom for protein annotation

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Bibliografiske detaljer
Hovedforfatter:	Ribeiro, Edward de Oliveira
Publication Date:	2005
Andre forfattere:	Zerlotini, Gustavo G., Lopes, Irving R. M., Ribeiro, Victor B. R., Melo, Melo, Alba Cristina Magalhães Alves de, Walter, Maria Emília Machado Telles, Costa, Marcos Mota, BIOFOCO Network
Format:	Article
Sprog:	eng
Source:	Repositório Institucional da UnB
Download full:	http://repositorio.unb.br/handle/10482/32103
Summary:	Interpro is a widely used tool for protein annotation in genome sequencing projects, demanding a large amount of computation and representing a huge time-consuming step. We present a strategy to execute programs using databases Pfam, PROSITE and ProDom of Interpro in a distributed environment using a Java-based messaging system. We developed a two-layer scheduling architecture of the distributed infrastructure. Then, we made experiments and analyzed the results. Our distributed system gave much better results than Interpro Pfam, PROSITE and ProDom running in a centralized platform. This approach seems to be appropriate and promising for highly demanding computational tools used for biological applications.

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