Dendritic cells : a double-edged sword in immune responses during chagas disease
সংরক্ষণ করুন:
| প্রধান লেখক: | |
|---|---|
| প্রকাশনার তারিখ: | 2016 |
| অন্যান্য লেখক: | , , , |
| বিন্যাস: | Article |
| ভাষা: | eng |
| সম্পদ: | Repositório Institucional da UnB |
| Download full: | http://repositorio.unb.br/handle/10482/23883 https://dx.doi.org/10.3389/fmicb.2016.01076 |
সংক্ষিপ্ত: | Dendritic cells (DCs) are the most important member of the antigen presenting cells group due to their ability to recognize antigen at the infection site and their high specialized antigen internalization capacity. These cells have central role in connecting the innate and adaptive immune responses against Trypanosoma cruzi, the causative agent of Chagas disease. These first line defense cells modulate host immune response depending on type, maturation level, cytokine milieu and DC receptor involved in the interactions with T. cruzi, influencing the development of the disease clinic forms. Here, we present a review of DCs–T. cruzi interactions both in human and murine models, pointing out the parasite ability to manipulate DCs activity for the purpose of evading innate immune response and assuring its own survival and persistence. |
অনুরূপ উপাদানগুলি: Dendritic cells : a double-edged sword in immune responses during chagas disease
- Validação do transcriptoma por meio da análise de expressão de genes de células dendríticas na presença de Trypanosoma cruzi
- Transcriptional remodeling patterns in murine dendritic cells infected with Paracoccidioides brasiliensis : more is not necessarily better
- Análise preliminar do transcriptoma de células dendríticas humanas após infecção por Trypanosoma cruzi
- Regulação da biologia de células dendríticas humanas por Escherichia coli uropatogênica (UPEC)
- Autoimmunity in Chagas' disease: immunomodulation of autoimmune and T. cruzi-specific immune responses
- Trypanosoma cruzi : antigen-receptor mediated endocytosis of antibody