Chemical composition, antioxidant activity and development of a facial serum formulation from the extract of Hancornia speciosa

• Autor(a) principal: Panontin, Juliane Farinelli
• Data de Publicação: 2022
• Outros Autores: Barbosa, Robson dos Santos, Isaac, Vera [UNESP], Seibert, Carla Simone, Scapin, Elisandra
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1080/14786419.2022.2053968; http://hdl.handle.net/11449/223725
• topic: anti-ageing; DPPH; Mangabeira; phenolic compounds; phytocosmetics

The goal of this work was to chemically characterise Hancornia speciosa extracts to develop an antioxidant serum formulation. Stem and bark extracts were prepared using 70% hydroethanol solution by Sohxlet and ultrasound assisted extraction. The content of total phenols, flavonoids, and antioxidant activity were evaluated, and chemical characterization was performed by HPLC -detector UV-VIS (SPD − 10 A). The formulation was developed with stem extract (0.250 mg/g) in hydroxyethylcellulose fluid gel. Stem extracts had higher total phenols and flavonoids, and higher antioxidant activity than bark extracts. The formulation presented low viscosity, a yellowish colour, 81.28% ± 0.14 of antioxidant activity. In the stability test, the physicochemical characteristics showed small variations, remaining more stable at a temperature of 5 °C, with an antioxidant activity of 64.81% ± 0.75. Therefore, the stem of H. speciosa has the potential to be used in antioxidant formulations.