TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO
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Publication Date: | 2024 |
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Format: | Article |
Language: | por |
Source: | Repositório Institucional da UNESP |
Download full: | http://dx.doi.org/10.1590/1808-1657v67n2p1772000 https://hdl.handle.net/11449/304703 |
Summary: | Mastitis is the generic name for inflammation of the mammary gland, no matter the cause, and it may be traumatic, toxic, allergic, metabolic or infectious, especially of bacterial origin. The process reduces milk production and changes the chemical composition of it, contributing to the decrease of its quality, turning into a possible problem for public health and for the dairy industry. The objective of this study was to evaluate the efficacy of bovine mastitis treatment using enrofloxacin and amoxicilin isolated or in association. Primiparous and multiparous cows in lactation were used, with subclinical mastitis diagnosed by CMT (+++ score), and others with clinical mastitis, diagnosed by positive black-bottom glass test. Microbiologic diagnostics was performed with 0.1 mL of each sample, in bovine blood-agar 10% and MacConkey agar, before and 21 days after the end of treatments in order to evaluate the microbiological recovery. Tests were performed to evaluate the sensitivity of each microorganism isolated to the drugs used in this study, and then the animals were treated by intramammary infusion after milking, in the morning and afternoon, during three consecutive days. The results obtained with the treatments with amoxicilin, enrofloxacin and the association of both drugs for the different microorganisms isolated (Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus agalactiae and Escherichia coli), in both subclinical or clinical cases, independently of the involved microorganism, were respectively 84.6% and 75.0%; 83.3% and 75.0%; 87.5% and 84.0% % of recovery, demonstrating the viability of their use in the treatment of mastitis,e specially when used in association, and the process was caused by Streptococcus agalactiae and Escherichia coli. |
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TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃOTREATMENT OF THE BOVINE MASTITIS WITH AMOXICILIN AND ENROFLOXACIN AS WELL AS THEIR ASSOCIATIONMastitisbovinetreatmentenrofloxacinamoxicilin.Mastitebovinatratamentoenrofloxacinaamoxicilina.Mastitis is the generic name for inflammation of the mammary gland, no matter the cause, and it may be traumatic, toxic, allergic, metabolic or infectious, especially of bacterial origin. The process reduces milk production and changes the chemical composition of it, contributing to the decrease of its quality, turning into a possible problem for public health and for the dairy industry. The objective of this study was to evaluate the efficacy of bovine mastitis treatment using enrofloxacin and amoxicilin isolated or in association. Primiparous and multiparous cows in lactation were used, with subclinical mastitis diagnosed by CMT (+++ score), and others with clinical mastitis, diagnosed by positive black-bottom glass test. Microbiologic diagnostics was performed with 0.1 mL of each sample, in bovine blood-agar 10% and MacConkey agar, before and 21 days after the end of treatments in order to evaluate the microbiological recovery. Tests were performed to evaluate the sensitivity of each microorganism isolated to the drugs used in this study, and then the animals were treated by intramammary infusion after milking, in the morning and afternoon, during three consecutive days. The results obtained with the treatments with amoxicilin, enrofloxacin and the association of both drugs for the different microorganisms isolated (Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus agalactiae and Escherichia coli), in both subclinical or clinical cases, independently of the involved microorganism, were respectively 84.6% and 75.0%; 83.3% and 75.0%; 87.5% and 84.0% % of recovery, demonstrating the viability of their use in the treatment of mastitis,e specially when used in association, and the process was caused by Streptococcus agalactiae and Escherichia coli.A mastite é a inflamação da glândula mamária independente de sua causa, portanto, traumática, tóxica, alérgica, metabólica e infecciosa, destacando-se as de origem bacteriana. Reduz a produção do leite e altera a sua composição química, contribuindo para a diminuição de sua qualidade, podendo se transformar em problema para a saúde pública e para a indústria leiteira. Objetivouse neste trabalho, avaliar a eficácia do tratamento da mastite bovina utilizando-se a enrofloxacina e a amoxicilina isoladas e em associação. Utilizaram-se vacas primíparas e multíparas, em plena lactação, com diagnóstico de mastite subclínica pelo CMT, escore +++, e casos de mastite clínica diagnosticadas pelo exame da caneca de fundo negro. Foi realizado o diagnóstico microbiológico cultivando-se 0,1mL de leite por amostra em meios ágar-sangue bovino a 10% e ágar MacConkey, previamente e 21 dias após o término do tratamento, para estimativa de cura microbiológica. Dos microrganismos isolados foi realizado o estudo de sensibilidade das drogas utilizadas, procedendose ao tratamento por infusão intramamária, após a ordenha da manhã e da tarde, durante três dias consecutivos. Obteve-se com os três tratamentos para os diferentes microrganismos envolvidos, ou seja: Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus agalactiae e Escherichia coli, tanto nos casos subclínicos como clínicos, independentemente do microrganismo envolvido, 84,6% e 75,0%; 83,3% e 75,0% e 87,5% e 84,0% de cura, respectivamente, nos tratamentos com amoxicilina, enrofloxacina e a associação de ambas, demonstrando a viabilidade destas no tratamento, ressaltando-se melhor ação quando os dois princípios medicamentosos estavam associados, com diferença significativa apontada pela prova não paramétrica de Kruskal-Wallis (H=80,26; p<0,005), especialmente quando as mastites eram causadas por Streptococcus agalactiae e Escherichia coli.Universidade Estadual Paulista “Julio Mesquita Filho”, FMVZUNESP, FMVZUniversidade Estadual Paulista “Julio Mesquita Filho”, FMVZUNESP, FMVZInstituto BiológicoUniversidade Estadual Paulista (UNESP)Langoni, H. [UNESP]Araújo, W.n. De [UNESP]Silva, A.v. Da [UNESP]Souza, L.c. De [UNESP]2025-04-29T19:35:45Z2024-09-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article177-180http://dx.doi.org/10.1590/1808-1657v67n2p1772000Arquivos do Instituto Biológico. Instituto Biológico, v. 67, n. 2, p. 177-180, 2024.0020-36531808-1657https://hdl.handle.net/11449/30470310.1590/1808-1657v67n2p1772000S1808-16572000000200177S1808-16572000000200177.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporArquivos do Instituto Biológicoinfo:eu-repo/semantics/openAccess2025-04-30T13:52:58Zoai:repositorio.unesp.br:11449/304703Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462025-04-30T13:52:58Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO TREATMENT OF THE BOVINE MASTITIS WITH AMOXICILIN AND ENROFLOXACIN AS WELL AS THEIR ASSOCIATION |
title |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO |
spellingShingle |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO Langoni, H. [UNESP] Mastitis bovine treatment enrofloxacin amoxicilin. Mastite bovina tratamento enrofloxacina amoxicilina. |
title_short |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO |
title_full |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO |
title_fullStr |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO |
title_full_unstemmed |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO |
title_sort |
TRATAMENTO DA MASTITE BOVINA COM AMOXICILINA E ENROFLOXACINA BEM COMO COM A SUA ASSOCIAÇÃO |
author |
Langoni, H. [UNESP] |
author_facet |
Langoni, H. [UNESP] Araújo, W.n. De [UNESP] Silva, A.v. Da [UNESP] Souza, L.c. De [UNESP] |
author_role |
author |
author2 |
Araújo, W.n. De [UNESP] Silva, A.v. Da [UNESP] Souza, L.c. De [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Langoni, H. [UNESP] Araújo, W.n. De [UNESP] Silva, A.v. Da [UNESP] Souza, L.c. De [UNESP] |
dc.subject.por.fl_str_mv |
Mastitis bovine treatment enrofloxacin amoxicilin. Mastite bovina tratamento enrofloxacina amoxicilina. |
topic |
Mastitis bovine treatment enrofloxacin amoxicilin. Mastite bovina tratamento enrofloxacina amoxicilina. |
description |
Mastitis is the generic name for inflammation of the mammary gland, no matter the cause, and it may be traumatic, toxic, allergic, metabolic or infectious, especially of bacterial origin. The process reduces milk production and changes the chemical composition of it, contributing to the decrease of its quality, turning into a possible problem for public health and for the dairy industry. The objective of this study was to evaluate the efficacy of bovine mastitis treatment using enrofloxacin and amoxicilin isolated or in association. Primiparous and multiparous cows in lactation were used, with subclinical mastitis diagnosed by CMT (+++ score), and others with clinical mastitis, diagnosed by positive black-bottom glass test. Microbiologic diagnostics was performed with 0.1 mL of each sample, in bovine blood-agar 10% and MacConkey agar, before and 21 days after the end of treatments in order to evaluate the microbiological recovery. Tests were performed to evaluate the sensitivity of each microorganism isolated to the drugs used in this study, and then the animals were treated by intramammary infusion after milking, in the morning and afternoon, during three consecutive days. The results obtained with the treatments with amoxicilin, enrofloxacin and the association of both drugs for the different microorganisms isolated (Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus agalactiae and Escherichia coli), in both subclinical or clinical cases, independently of the involved microorganism, were respectively 84.6% and 75.0%; 83.3% and 75.0%; 87.5% and 84.0% % of recovery, demonstrating the viability of their use in the treatment of mastitis,e specially when used in association, and the process was caused by Streptococcus agalactiae and Escherichia coli. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-09-30 2025-04-29T19:35:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1808-1657v67n2p1772000 Arquivos do Instituto Biológico. Instituto Biológico, v. 67, n. 2, p. 177-180, 2024. 0020-3653 1808-1657 https://hdl.handle.net/11449/304703 10.1590/1808-1657v67n2p1772000 S1808-16572000000200177 S1808-16572000000200177.pdf |
url |
http://dx.doi.org/10.1590/1808-1657v67n2p1772000 https://hdl.handle.net/11449/304703 |
identifier_str_mv |
Arquivos do Instituto Biológico. Instituto Biológico, v. 67, n. 2, p. 177-180, 2024. 0020-3653 1808-1657 10.1590/1808-1657v67n2p1772000 S1808-16572000000200177 S1808-16572000000200177.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Arquivos do Instituto Biológico |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
177-180 |
dc.publisher.none.fl_str_mv |
Instituto Biológico |
publisher.none.fl_str_mv |
Instituto Biológico |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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1834482754326102016 |