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Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering

Bibliographic Details
Main Author: Barbosa, Lucas
Publication Date: 2023
Other Authors: Oliveira, Rodrigo L.M.S., De Macedo, Erenilda F., Hurtado, Carolina R., Ramos, Lucas de P. [UNESP], Oliveira, Luciane D. [UNESP], Conceição, Katia, Tada, Dayane B., Trichês, Eliandra de S.
Format: Book part
Language: eng
Source: Repositório Institucional da UNESP
Download full: http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-X
http://hdl.handle.net/11449/247432
Summary: This chapter provides an overview about some innovative strategies to functionalize calcium phosphate scaffolds’ surfaces by using antimicrobial agents to combat osteomyelitis. The scaffolds can be obtained by different techniques and must fulfill some requirements, including open and interconnected porosity, mechanical and biological properties, and biomaterial requirements. Also, special attention was given to understanding the mechanism of action of antimicrobial agents (antibiotics, nanoparticles (NPs), and photosensitizers (PS)) that is essential to enhance the development of efficient antimicrobial scaffolds. Finally, this chapter reports on recent results obtained by our group regarding the development of β-tricalcium phosphate (β-TCP) scaffolds with antibacterial properties afforded by the incorporation of silver nanoparticles and methylene blue.
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spelling Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineeringAntimicrobial agentsBone tissue engineeringCalcium phosphatesMultifunctional scaffoldsThis chapter provides an overview about some innovative strategies to functionalize calcium phosphate scaffolds’ surfaces by using antimicrobial agents to combat osteomyelitis. The scaffolds can be obtained by different techniques and must fulfill some requirements, including open and interconnected porosity, mechanical and biological properties, and biomaterial requirements. Also, special attention was given to understanding the mechanism of action of antimicrobial agents (antibiotics, nanoparticles (NPs), and photosensitizers (PS)) that is essential to enhance the development of efficient antimicrobial scaffolds. Finally, this chapter reports on recent results obtained by our group regarding the development of β-tricalcium phosphate (β-TCP) scaffolds with antibacterial properties afforded by the incorporation of silver nanoparticles and methylene blue.Federal University of São Paulo UNIFESP, SPFederal Institute of São Paulo IFSP, SPSão Paulo State University UNESP, SPSão Paulo State University UNESP, SPUniversidade de São Paulo (USP)IFSPUniversidade Estadual Paulista (UNESP)Barbosa, LucasOliveira, Rodrigo L.M.S.De Macedo, Erenilda F.Hurtado, Carolina R.Ramos, Lucas de P. [UNESP]Oliveira, Luciane D. [UNESP]Conceição, KatiaTada, Dayane B.Trichês, Eliandra de S.2023-07-29T13:15:54Z2023-07-29T13:15:54Z2023-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart289-322http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-XSurface Modification and Functionalization of Ceramic Composites, p. 289-322.http://hdl.handle.net/11449/24743210.1016/B978-0-323-85883-0.00017-X2-s2.0-85160178236Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengSurface Modification and Functionalization of Ceramic Compositesinfo:eu-repo/semantics/openAccess2023-07-29T13:15:54Zoai:repositorio.unesp.br:11449/247432Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462023-07-29T13:15:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
title Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
spellingShingle Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
Barbosa, Lucas
Antimicrobial agents
Bone tissue engineering
Calcium phosphates
Multifunctional scaffolds
title_short Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
title_full Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
title_fullStr Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
title_full_unstemmed Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
title_sort Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
author Barbosa, Lucas
author_facet Barbosa, Lucas
Oliveira, Rodrigo L.M.S.
De Macedo, Erenilda F.
Hurtado, Carolina R.
Ramos, Lucas de P. [UNESP]
Oliveira, Luciane D. [UNESP]
Conceição, Katia
Tada, Dayane B.
Trichês, Eliandra de S.
author_role author
author2 Oliveira, Rodrigo L.M.S.
De Macedo, Erenilda F.
Hurtado, Carolina R.
Ramos, Lucas de P. [UNESP]
Oliveira, Luciane D. [UNESP]
Conceição, Katia
Tada, Dayane B.
Trichês, Eliandra de S.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
IFSP
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Barbosa, Lucas
Oliveira, Rodrigo L.M.S.
De Macedo, Erenilda F.
Hurtado, Carolina R.
Ramos, Lucas de P. [UNESP]
Oliveira, Luciane D. [UNESP]
Conceição, Katia
Tada, Dayane B.
Trichês, Eliandra de S.
dc.subject.por.fl_str_mv Antimicrobial agents
Bone tissue engineering
Calcium phosphates
Multifunctional scaffolds
topic Antimicrobial agents
Bone tissue engineering
Calcium phosphates
Multifunctional scaffolds
description This chapter provides an overview about some innovative strategies to functionalize calcium phosphate scaffolds’ surfaces by using antimicrobial agents to combat osteomyelitis. The scaffolds can be obtained by different techniques and must fulfill some requirements, including open and interconnected porosity, mechanical and biological properties, and biomaterial requirements. Also, special attention was given to understanding the mechanism of action of antimicrobial agents (antibiotics, nanoparticles (NPs), and photosensitizers (PS)) that is essential to enhance the development of efficient antimicrobial scaffolds. Finally, this chapter reports on recent results obtained by our group regarding the development of β-tricalcium phosphate (β-TCP) scaffolds with antibacterial properties afforded by the incorporation of silver nanoparticles and methylene blue.
publishDate 2023
dc.date.none.fl_str_mv 2023-07-29T13:15:54Z
2023-07-29T13:15:54Z
2023-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bookPart
format bookPart
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-X
Surface Modification and Functionalization of Ceramic Composites, p. 289-322.
http://hdl.handle.net/11449/247432
10.1016/B978-0-323-85883-0.00017-X
2-s2.0-85160178236
url http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-X
http://hdl.handle.net/11449/247432
identifier_str_mv Surface Modification and Functionalization of Ceramic Composites, p. 289-322.
10.1016/B978-0-323-85883-0.00017-X
2-s2.0-85160178236
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Surface Modification and Functionalization of Ceramic Composites
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 289-322
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1834483850120527872

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