Immunomodulatory effect of glucan on the response to experimental antirabies vaccination
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 1993 |
| Outros Autores: | , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| Texto Completo: | http://dx.doi.org/10.1590/S0036-46651993000500008 http://repositorio.unifesp.br/handle/11600/327 |
Resumo: | The objective of lhe present study was to determine the stimulatory response to antirabies vaccination promoted by glucan in mice. Glucan increased both resistance to infection and antibody titres and this effect was more evident when glucan was used at dose of 0.5 mg, administered intraperitoneally before, during and after immunization and when the challenge virus was applied to the foot-pad. |
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Immunomodulatory effect of glucan on the response to experimental antirabies vaccinationEfeito imunomodulatório da glucana na resposta à vacinação anti-rábica experimentalGlucanAntirabies vaccinationRabiesThe objective of lhe present study was to determine the stimulatory response to antirabies vaccination promoted by glucan in mice. Glucan increased both resistance to infection and antibody titres and this effect was more evident when glucan was used at dose of 0.5 mg, administered intraperitoneally before, during and after immunization and when the challenge virus was applied to the foot-pad.No presente trabalho verificou-se a atividade estimuladora da resposta à vacinação anti-rábica experimental determinada pela glucana em camundongos. Esta atividade pôde ser detectada por aumento da resistência à infecção e pela resposta imune mais intensa em termos de títulos de anticorpos. Estes resultados foram mais evidentes quando a glucana foi utilizada em doses de 0.5mg, administrada por via i.p., antes, durante e após a imunização e o desafio feito no coxim plantar da pata posterior.Escola Paulista de Medicina Disciplina de ImunologiaInstituto PasteurUNIFESP, EPM, Disciplina de ImunologiaSciELOConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Instituto de Medicina TropicalUniversidade Federal de São Paulo (UNIFESP)Instituto PasteurTino, Milene S. [UNIFESP]Carrieri, Maria L.Zanetti, Carlos RMendes, Nelson Figueiredo [UNIFESP]Pereira, Octavio A.c.2015-06-14T13:24:24Z2015-06-14T13:24:24Z1993-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion431-435application/pdfhttp://dx.doi.org/10.1590/S0036-46651993000500008Revista do Instituto de Medicina Tropical de São Paulo. Instituto de Medicina Tropical, v. 35, n. 5, p. 431-435, 1993.10.1590/S0036-46651993000500008S0036-46651993000500008.pdf0036-4665S0036-46651993000500008http://repositorio.unifesp.br/handle/11600/327engRevista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T19:44:59Zoai:repositorio.unifesp.br/:11600/327Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T19:44:59Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination Efeito imunomodulatório da glucana na resposta à vacinação anti-rábica experimental |
| title |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination |
| spellingShingle |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination Tino, Milene S. [UNIFESP] Glucan Antirabies vaccination Rabies |
| title_short |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination |
| title_full |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination |
| title_fullStr |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination |
| title_full_unstemmed |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination |
| title_sort |
Immunomodulatory effect of glucan on the response to experimental antirabies vaccination |
| author |
Tino, Milene S. [UNIFESP] |
| author_facet |
Tino, Milene S. [UNIFESP] Carrieri, Maria L. Zanetti, Carlos R Mendes, Nelson Figueiredo [UNIFESP] Pereira, Octavio A.c. |
| author_role |
author |
| author2 |
Carrieri, Maria L. Zanetti, Carlos R Mendes, Nelson Figueiredo [UNIFESP] Pereira, Octavio A.c. |
| author2_role |
author author author author |
| dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Instituto Pasteur |
| dc.contributor.author.fl_str_mv |
Tino, Milene S. [UNIFESP] Carrieri, Maria L. Zanetti, Carlos R Mendes, Nelson Figueiredo [UNIFESP] Pereira, Octavio A.c. |
| dc.subject.por.fl_str_mv |
Glucan Antirabies vaccination Rabies |
| topic |
Glucan Antirabies vaccination Rabies |
| description |
The objective of lhe present study was to determine the stimulatory response to antirabies vaccination promoted by glucan in mice. Glucan increased both resistance to infection and antibody titres and this effect was more evident when glucan was used at dose of 0.5 mg, administered intraperitoneally before, during and after immunization and when the challenge virus was applied to the foot-pad. |
| publishDate |
1993 |
| dc.date.none.fl_str_mv |
1993-10-01 2015-06-14T13:24:24Z 2015-06-14T13:24:24Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0036-46651993000500008 Revista do Instituto de Medicina Tropical de São Paulo. Instituto de Medicina Tropical, v. 35, n. 5, p. 431-435, 1993. 10.1590/S0036-46651993000500008 S0036-46651993000500008.pdf 0036-4665 S0036-46651993000500008 http://repositorio.unifesp.br/handle/11600/327 |
| url |
http://dx.doi.org/10.1590/S0036-46651993000500008 http://repositorio.unifesp.br/handle/11600/327 |
| identifier_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo. Instituto de Medicina Tropical, v. 35, n. 5, p. 431-435, 1993. 10.1590/S0036-46651993000500008 S0036-46651993000500008.pdf 0036-4665 S0036-46651993000500008 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
431-435 application/pdf |
| dc.publisher.none.fl_str_mv |
Instituto de Medicina Tropical |
| publisher.none.fl_str_mv |
Instituto de Medicina Tropical |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
| instname_str |
Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
| _version_ |
1841453699093757952 |