Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil

Bibliographic Details
Main Author: Vieira, Sarah Cristina Fontes
Publication Date: 2011
Other Authors: Gurgel, Ricardo Queiroz, Kirby, Andrew, Barreto, Isis Pinheiro, Souza, Liane Desiderio de, Oliveira, Oderlan Carvalho, Correia, Jailson de Barros, Dove, Winifred, Cunliffe, Nigel A., Cuevas, Luis E.
Format: Article
Language: eng
Source: Repositório Institucional da UFS
Download full: https://ri.ufs.br/jspui/handle/riufs/23237
Summary: Rio de Janeiro
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spelling Vieira, Sarah Cristina FontesGurgel, Ricardo QueirozKirby, AndrewBarreto, Isis PinheiroSouza, Liane Desiderio deOliveira, Oderlan CarvalhoCorreia, Jailson de BarrosDove, WinifredCunliffe, Nigel A.Cuevas, Luis E.2025-09-24T17:28:51Z2025-09-24T17:28:51Z2011-05VIEIRA, S. C. F. et al. Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 3, p. 330-334, maio 2011. Disponível em: https://www.scielo.br/j/mioc/a/BxfxrhkQSkdZLLMP9dLh44x/?lang=en. Acesso em: 24 set. 2025.1678-8060https://ri.ufs.br/jspui/handle/riufs/23237Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)engInstituto Oswaldo Cruz - Ministério da SaúdeMemórias do Instituto Oswaldo CruzDiarrhoeaRotavirusVaccineCohortChildrenBrazilAcute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRio de JaneiroRotavirus is an important cause of childhood diarrhoea. A monovalent rotavirus vaccine (Rotarix®) was introduced into the Immunization Program of Brazil in 2006. In this study, we describe the incidence and burden of disease of rotavirus diarrhoea in two cohorts of children (vaccinated and unvaccinated). We followed two groups of 250 children under one year old, who were enrolled in December 2006 from a low-income residential area in Northeast Brazil. The children were monitored every two weeks for two years. Stool samples from children with diarrhoea were examined for the presence of rotavirus. Rotaviruses were genotyped using real time-polymerase chain reaction. The mean numbers of all-cause diarrhoea episodes/child (adjusted for age) in the first year were 0.87 and 0.84, in vaccinated and unvaccinated children, respectively. During the second year, the number of episodes/ child decreased to 0.52 and 0.42. Only 16 (4.9%) of 330 stool samples were rotavirus-positive (10 vaccinated and 6 unvaccinated children) and only P[4]G2 rotaviruses were identified. All-cause diarrhoea episodes were more severe in unvaccinated children in the first year of age (p < 0.05), while vaccinated children had more severe episodes 18 months after vaccination. 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dc.title.pt_BR.fl_str_mv Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
title Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
spellingShingle Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
Vieira, Sarah Cristina Fontes
Diarrhoea
Rotavirus
Vaccine
Cohort
Children
Brazil
title_short Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
title_full Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
title_fullStr Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
title_full_unstemmed Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
title_sort Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil
author Vieira, Sarah Cristina Fontes
author_facet Vieira, Sarah Cristina Fontes
Gurgel, Ricardo Queiroz
Kirby, Andrew
Barreto, Isis Pinheiro
Souza, Liane Desiderio de
Oliveira, Oderlan Carvalho
Correia, Jailson de Barros
Dove, Winifred
Cunliffe, Nigel A.
Cuevas, Luis E.
author_role author
author2 Gurgel, Ricardo Queiroz
Kirby, Andrew
Barreto, Isis Pinheiro
Souza, Liane Desiderio de
Oliveira, Oderlan Carvalho
Correia, Jailson de Barros
Dove, Winifred
Cunliffe, Nigel A.
Cuevas, Luis E.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vieira, Sarah Cristina Fontes
Gurgel, Ricardo Queiroz
Kirby, Andrew
Barreto, Isis Pinheiro
Souza, Liane Desiderio de
Oliveira, Oderlan Carvalho
Correia, Jailson de Barros
Dove, Winifred
Cunliffe, Nigel A.
Cuevas, Luis E.
dc.subject.eng.fl_str_mv Diarrhoea
Rotavirus
Vaccine
Cohort
Children
Brazil
topic Diarrhoea
Rotavirus
Vaccine
Cohort
Children
Brazil
description Rio de Janeiro
publishDate 2011
dc.date.issued.fl_str_mv 2011-05
dc.date.accessioned.fl_str_mv 2025-09-24T17:28:51Z
dc.date.available.fl_str_mv 2025-09-24T17:28:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VIEIRA, S. C. F. et al. Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 3, p. 330-334, maio 2011. Disponível em: https://www.scielo.br/j/mioc/a/BxfxrhkQSkdZLLMP9dLh44x/?lang=en. Acesso em: 24 set. 2025.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/jspui/handle/riufs/23237
dc.identifier.issn.none.fl_str_mv 1678-8060
dc.identifier.license.pt_BR.fl_str_mv Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)
identifier_str_mv VIEIRA, S. C. F. et al. Acute diarrhoea in a community cohort of children who received an oral rotavirus vaccine in Northeast Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 3, p. 330-334, maio 2011. Disponível em: https://www.scielo.br/j/mioc/a/BxfxrhkQSkdZLLMP9dLh44x/?lang=en. Acesso em: 24 set. 2025.
1678-8060
Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)
url https://ri.ufs.br/jspui/handle/riufs/23237
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Memórias do Instituto Oswaldo Cruz
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz - Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz - Ministério da Saúde
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFS
instname:Universidade Federal de Sergipe (UFS)
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