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Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura

Bibliographic Details
Main Author: Andrade, Géssica de Oliveira
Publication Date: 2018
Other Authors: Sousa, Grazyele Santana de
Format: Bachelor thesis
Language: por
Source: Repositório Institucional da UFS
Download full: http://ri.ufs.br/jspui/handle/riufs/10099
Summary: Oral squamous cell carcinoma (CCEO) is one of the most common worldwide, accounting for an estimated 1-2% of deaths caused by cancer. In CCEO, matrix metalloproteinases (MMPs) are associated with extracellular matrix degradation (ECM). The objective of the present study is to perform a literature review on the main MMPs and their association to the CCEO. The survey was conducted in the PubMed database between February and August 2018. The MMP-2 and -9 merit notoriety for collaborating in the invasion and metastasis processes. These enzymes are suggested as a prognostic factor, mainly detecting the invasion capacity of the lesions.
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spelling Andrade, Géssica de OliveiraSousa, Grazyele Santana deMatos, Felipe Rodrigues de2018-12-11T14:08:05Z2018-12-11T14:08:05Z2018-09-03ANDRADE, Géssica de Oliveira; SOUSA, Grazyele Santana de. Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral:uma revisão de literatura. 2018. Trabalho de Conclusão de Curso (Graduação em Odontologia) - Universidade Federal de Sergipe, Lagarto, 2018.http://ri.ufs.br/jspui/handle/riufs/10099Oral squamous cell carcinoma (CCEO) is one of the most common worldwide, accounting for an estimated 1-2% of deaths caused by cancer. In CCEO, matrix metalloproteinases (MMPs) are associated with extracellular matrix degradation (ECM). The objective of the present study is to perform a literature review on the main MMPs and their association to the CCEO. The survey was conducted in the PubMed database between February and August 2018. The MMP-2 and -9 merit notoriety for collaborating in the invasion and metastasis processes. These enzymes are suggested as a prognostic factor, mainly detecting the invasion capacity of the lesions.O carcinoma de células escamosas oral (CCEO) é um dos mais comuns em todo o mundo, responsável por uma estimativa de 1-2% das mortes causadas por câncer. No CCEO, as metaloproteinases da matriz (MMPs), estão associadas à degradação da matriz extracelular (MEC). O objetivo do presente trabalho foi realizar uma revisão de literatura a respeito das principais MMPs e a sua associação ao CCEO. A pesquisa foi realizada na base de dados PubMed, entre fevereiro e agosto de 2018. As MMP-2 e -9 merecem notoriedade por colaborarem nas atividades de invasão e metástase. Essas enzimas são sugeridas como fator prognóstico, apontando, sobretudo a capacidade de invasão das lesões.Lagarto, SEporCarcinoma de células escamosasBocaCâncerCarcinoma de células escamosas oralMMPsOral squamous cell carcinomaInfluência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literaturainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUFSDOL - Departamento de Odontologia – Lagarto - Presencialreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTEXTGÉSSICA_OLIVEIRA_ANDRADE&GRAZYELE_SANTANA_DE_SOUSA.pdf.txtGÉSSICA_OLIVEIRA_ANDRADE&GRAZYELE_SANTANA_DE_SOUSA.pdf.txtExtracted texttext/plain29868https://ri.ufs.br/jspui/bitstream/riufs/10099/3/G%c3%89SSICA_OLIVEIRA_ANDRADE%26GRAZYELE_SANTANA_DE_SOUSA.pdf.txt8afedaac3d17fc0517de6c5df503ceaeMD53THUMBNAILGÉSSICA_OLIVEIRA_ANDRADE&GRAZYELE_SANTANA_DE_SOUSA.pdf.jpgGÉSSICA_OLIVEIRA_ANDRADE&GRAZYELE_SANTANA_DE_SOUSA.pdf.jpgGenerated Thumbnailimage/jpeg1235https://ri.ufs.br/jspui/bitstream/riufs/10099/4/G%c3%89SSICA_OLIVEIRA_ANDRADE%26GRAZYELE_SANTANA_DE_SOUSA.pdf.jpg97ab6ec5f2eee47f11b73566eb1b2937MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/10099/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51ORIGINALGÉSSICA_OLIVEIRA_ANDRADE&GRAZYELE_SANTANA_DE_SOUSA.pdfGÉSSICA_OLIVEIRA_ANDRADE&GRAZYELE_SANTANA_DE_SOUSA.pdfapplication/pdf585525https://ri.ufs.br/jspui/bitstream/riufs/10099/2/G%c3%89SSICA_OLIVEIRA_ANDRADE%26GRAZYELE_SANTANA_DE_SOUSA.pdf26c047f1d77fbb72a4fbd49e0ae0dcf5MD52riufs/100992018-12-11 11:08:05.523oai:oai:ri.ufs.br:repo_01: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2018-12-11T14:08:05Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
title Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
spellingShingle Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
Andrade, Géssica de Oliveira
Carcinoma de células escamosas
Boca
Câncer
Carcinoma de células escamosas oral
MMPs
Oral squamous cell carcinoma
title_short Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
title_full Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
title_fullStr Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
title_full_unstemmed Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
title_sort Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral: uma revisão de literatura
author Andrade, Géssica de Oliveira
author_facet Andrade, Géssica de Oliveira
Sousa, Grazyele Santana de
author_role author
author2 Sousa, Grazyele Santana de
author2_role author
dc.contributor.author.fl_str_mv Andrade, Géssica de Oliveira
Sousa, Grazyele Santana de
dc.contributor.advisor1.fl_str_mv Matos, Felipe Rodrigues de
contributor_str_mv Matos, Felipe Rodrigues de
dc.subject.por.fl_str_mv Carcinoma de células escamosas
Boca
Câncer
Carcinoma de células escamosas oral
MMPs
topic Carcinoma de células escamosas
Boca
Câncer
Carcinoma de células escamosas oral
MMPs
Oral squamous cell carcinoma
dc.subject.eng.fl_str_mv Oral squamous cell carcinoma
description Oral squamous cell carcinoma (CCEO) is one of the most common worldwide, accounting for an estimated 1-2% of deaths caused by cancer. In CCEO, matrix metalloproteinases (MMPs) are associated with extracellular matrix degradation (ECM). The objective of the present study is to perform a literature review on the main MMPs and their association to the CCEO. The survey was conducted in the PubMed database between February and August 2018. The MMP-2 and -9 merit notoriety for collaborating in the invasion and metastasis processes. These enzymes are suggested as a prognostic factor, mainly detecting the invasion capacity of the lesions.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-12-11T14:08:05Z
dc.date.available.fl_str_mv 2018-12-11T14:08:05Z
dc.date.issued.fl_str_mv 2018-09-03
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bachelorThesis
format bachelorThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Géssica de Oliveira; SOUSA, Grazyele Santana de. Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral:uma revisão de literatura. 2018. Trabalho de Conclusão de Curso (Graduação em Odontologia) - Universidade Federal de Sergipe, Lagarto, 2018.
dc.identifier.uri.fl_str_mv http://ri.ufs.br/jspui/handle/riufs/10099
identifier_str_mv ANDRADE, Géssica de Oliveira; SOUSA, Grazyele Santana de. Influência das metaloproteinases da matriz extracelular no carcinoma de células escamosas oral:uma revisão de literatura. 2018. Trabalho de Conclusão de Curso (Graduação em Odontologia) - Universidade Federal de Sergipe, Lagarto, 2018.
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.initials.fl_str_mv UFS
dc.publisher.department.fl_str_mv DOL - Departamento de Odontologia – Lagarto - Presencial
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