Wernicke’s encephalopathy in a patient with non- Hodgkin’s lymphoma post-Autologous HSCT

• Main Author: Leitão, João Paulo de Vasconcelos
• Publication Date: 2018
• Other Authors: Lemes, Romélia Pinheiro Gonçalves, Barbosa, Maritza Cavalcante, Araújo, Beatriz Stela Gomes de Souza Pitombeira, Barroso, Karine Sampaio Nunes, Kaufman, Jacques, Santos, Talyta Ellen de Jesus dos, Moura, Anna Thawanny Gadelha, Barreto, André Rodrigues Façanha, Duarte, Fernando Barroso
• Format: Article
• Language: eng
• Source: Repositório Institucional da Universidade Federal do Ceará (UFC)
• Download full: http://www.repositorio.ufc.br/handle/riufc/40666
• topic: Encefalopatia de Wernicke; Wernicke Encephalopathy; Thiamine Deficiency; Deficiência de Tiamina

Wernick’s Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely considered in patients submitted to this procedure. Considering that, the manuscript reports the clinical characteristics and the possible factors that predisposed the occurrence of WE in a patient with non-Hodgkin’s lymphoma post-Autologous HSCT. We conclude that WE should be considered in patients submitted to autologous HSCT associated with prolonged use of TPN and malnutrition.