Central administration of zinc reduces salt intake in rats

Bibliographic Details
Main Author: Silva, Emilio de Castro e
Publication Date: 2002
Other Authors: Ferreira, Hilda Silva, Magrani, Janeide, Santamaria, Guillermo Fernandez, Fregoneze, Josmara Bartolomei
Format: Article
Language: eng
Source: Repositório Institucional da UFBA
Download full: http://www.repositorio.ufba.br/ri/handle/ri/7537
Summary: Texto completo: acesso restrito. p. 531–539
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spelling Silva, Emilio de Castro eFerreira, Hilda SilvaMagrani, JaneideSantamaria, Guillermo FernandezFregoneze, Josmara BartolomeiSilva, Emilio de Castro eFerreira, Hilda SilvaMagrani, JaneideSantamaria, Guillermo FernandezFregoneze, Josmara Bartolomei2012-12-14T13:39:22Z2002-04-010031-9384http://www.repositorio.ufba.br/ri/handle/ri/7537v. 75, n. 4Texto completo: acesso restrito. p. 531–539The aim of the present study was to investigate the effect of third ventricle injections of zinc on salt intake in rats in the three different experimental models where sodium appetite is increased: fluid deprivation, central angiotensinergic stimulation and sodium depletion. Adult Wistar male rats received third ventricle injections of Zn(Ac)2 in three different doses (0.03, 0.3 and 3.0 nmol/rat). Central angiotensinergic stimulation was achieved by third ventricle injections of angiotensin II in the dose of 25 ng/rat 30 min before central zinc administration. As expected, fluid deprivation, central angiotensinergic stimulation and sodium depletion significantly increased sodium appetite. Water intake was also enhanced after fluid deprivation and central angiotensinergic stimulation. After sodium depletion, no increase in water intake was observed. Third ventricle injections of zinc inhibited salt intake in all three experimental models studied. Water intake was also inhibited by central zinc administration after fluid deprivation and central angiotensinergic stimulation. Conversely, third ventricle injections of zinc were unable to modify food intake or body temperature. It is suggested that zinc, acting on central structures related to the control of body fluid homeostasis, inhibits the drive for salt intake that is normally observed during fluid deprivation, central angiotensinergic stimulation and sodium depletion.Submitted by Suelen Reis (suelen_suzane@hotmail.com) on 2012-12-14T13:39:22Z No. of bitstreams: 1 1-s2.0-S003193840200656X-main.pdf: 264388 bytes, checksum: 38fc92e83c6962ee79e1db7971739a15 (MD5)Made available in DSpace on 2012-12-14T13:39:22Z (GMT). No. of bitstreams: 1 1-s2.0-S003193840200656X-main.pdf: 264388 bytes, checksum: 38fc92e83c6962ee79e1db7971739a15 (MD5) Previous issue date: 2002-04-01http://dx.doi.org/10.1016/S0031-9384(02)00656-Xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAZincSalt intakeWater intakeSalt depletionAngiotensin IICentral administration of zinc reduces salt intake in ratsPhysiology and Behaviorinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL1-s2.0-S003193840200656X-main.pdf1-s2.0-S003193840200656X-main.pdfapplication/pdf264388https://repositorio.ufba.br/bitstream/ri/7537/1/1-s2.0-S003193840200656X-main.pdf38fc92e83c6962ee79e1db7971739a15MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/7537/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT1-s2.0-S003193840200656X-main.pdf.txt1-s2.0-S003193840200656X-main.pdf.txtExtracted texttext/plain40660https://repositorio.ufba.br/bitstream/ri/7537/3/1-s2.0-S003193840200656X-main.pdf.txt11d9e1e25b5fd1246974a6aced56691eMD53ri/75372022-07-05 14:03:19.674oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestrepositorio@ufba.bropendoar:19322022-07-05T17:03:19Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Central administration of zinc reduces salt intake in rats
dc.title.alternative.pt_BR.fl_str_mv Physiology and Behavior
title Central administration of zinc reduces salt intake in rats
spellingShingle Central administration of zinc reduces salt intake in rats
Silva, Emilio de Castro e
Zinc
Salt intake
Water intake
Salt depletion
Angiotensin II
title_short Central administration of zinc reduces salt intake in rats
title_full Central administration of zinc reduces salt intake in rats
title_fullStr Central administration of zinc reduces salt intake in rats
title_full_unstemmed Central administration of zinc reduces salt intake in rats
title_sort Central administration of zinc reduces salt intake in rats
author Silva, Emilio de Castro e
author_facet Silva, Emilio de Castro e
Ferreira, Hilda Silva
Magrani, Janeide
Santamaria, Guillermo Fernandez
Fregoneze, Josmara Bartolomei
author_role author
author2 Ferreira, Hilda Silva
Magrani, Janeide
Santamaria, Guillermo Fernandez
Fregoneze, Josmara Bartolomei
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Emilio de Castro e
Ferreira, Hilda Silva
Magrani, Janeide
Santamaria, Guillermo Fernandez
Fregoneze, Josmara Bartolomei
Silva, Emilio de Castro e
Ferreira, Hilda Silva
Magrani, Janeide
Santamaria, Guillermo Fernandez
Fregoneze, Josmara Bartolomei
dc.subject.por.fl_str_mv Zinc
Salt intake
Water intake
Salt depletion
Angiotensin II
topic Zinc
Salt intake
Water intake
Salt depletion
Angiotensin II
description Texto completo: acesso restrito. p. 531–539
publishDate 2002
dc.date.issued.fl_str_mv 2002-04-01
dc.date.accessioned.fl_str_mv 2012-12-14T13:39:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/7537
dc.identifier.issn.none.fl_str_mv 0031-9384
dc.identifier.number.pt_BR.fl_str_mv v. 75, n. 4
identifier_str_mv 0031-9384
v. 75, n. 4
url http://www.repositorio.ufba.br/ri/handle/ri/7537
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/S0031-9384(02)00656-X
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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