Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes

Bibliographic Details
Main Author: Rady,Mohamed Ibrahim
Publication Date: 2009
Format: Article
Language: eng
Source: Brazilian Archives of Biology and Technology
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008
Summary: The present study aimed to evaluate the histological changes and adverse effects on the total protein and general carbohydrates in the lung and small intestine of guinea pig "Cavia porcellus" induced by the exposure to sub lethal doses of the organophosphate insecticide diazinon. Primarily, diazinon insecticide oral LD50 was investigated after administrating orally different doses in guinea pig and was determined as 213 mg/Kg bw., the animals exposed to sub lethal doses of this insecticide revealed histological changes in both lung and intestine in a dose dependent manner. Also, significant decrease in the total protein and general carbohydrates in the lung and intestine were mostly observed, especially with the higher doses of the insecticide in comparison with control group.
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spelling Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changesDiazinonGuinea pigLungIntestineThe present study aimed to evaluate the histological changes and adverse effects on the total protein and general carbohydrates in the lung and small intestine of guinea pig "Cavia porcellus" induced by the exposure to sub lethal doses of the organophosphate insecticide diazinon. Primarily, diazinon insecticide oral LD50 was investigated after administrating orally different doses in guinea pig and was determined as 213 mg/Kg bw., the animals exposed to sub lethal doses of this insecticide revealed histological changes in both lung and intestine in a dose dependent manner. Also, significant decrease in the total protein and general carbohydrates in the lung and intestine were mostly observed, especially with the higher doses of the insecticide in comparison with control group.Instituto de Tecnologia do Paraná - Tecpar2009-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008Brazilian Archives of Biology and Technology v.52 n.2 2009reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132009000200008info:eu-repo/semantics/openAccessRady,Mohamed Ibrahimeng2009-05-06T00:00:00Zoai:scielo:S1516-89132009000200008Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2009-05-06T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
title Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
spellingShingle Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
Rady,Mohamed Ibrahim
Diazinon
Guinea pig
Lung
Intestine
title_short Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
title_full Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
title_fullStr Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
title_full_unstemmed Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
title_sort Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
author Rady,Mohamed Ibrahim
author_facet Rady,Mohamed Ibrahim
author_role author
dc.contributor.author.fl_str_mv Rady,Mohamed Ibrahim
dc.subject.por.fl_str_mv Diazinon
Guinea pig
Lung
Intestine
topic Diazinon
Guinea pig
Lung
Intestine
description The present study aimed to evaluate the histological changes and adverse effects on the total protein and general carbohydrates in the lung and small intestine of guinea pig "Cavia porcellus" induced by the exposure to sub lethal doses of the organophosphate insecticide diazinon. Primarily, diazinon insecticide oral LD50 was investigated after administrating orally different doses in guinea pig and was determined as 213 mg/Kg bw., the animals exposed to sub lethal doses of this insecticide revealed histological changes in both lung and intestine in a dose dependent manner. Also, significant decrease in the total protein and general carbohydrates in the lung and intestine were mostly observed, especially with the higher doses of the insecticide in comparison with control group.
publishDate 2009
dc.date.none.fl_str_mv 2009-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132009000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.52 n.2 2009
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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