Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications

Bibliographic Details
Main Author: Fernández-Lodeiro, Adrián
Publication Date: 2021
Other Authors: Djafari, Jamila, Fernández-Lodeiro, Javier, Duarte, Maria Paula, Mauricio, Elisabete Muchagato, Capelo-Martínez, José Luis, Lodeiro, Carlos
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/129525
Summary: POCI-01-0145-FEDER—007265 contract under DL57 SFRH/BD/52528/2014
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spelling Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applicationsAntibacterial activityGold nanoparticlesGold nanorodMesoporous silicaMethylene blueChemical Engineering(all)Materials Science(all)POCI-01-0145-FEDER—007265 contract under DL57 SFRH/BD/52528/2014In this work, the successful preparation and characterization of gold nanorods (AuNRs) coated with a mesoporous silica shell (AuNRs@Simes) was achieved. Conjugation with methylene blue (MB) as a model drug using ultrasound-stimulated loading has been explored for further application in light-mediated antibacterial studies. Lyophilization of this conjugated nanosystem was analyzed using trehalose (TRH) as a cryogenic protector. The obtained stable dry formulation shows potent antimicrobial activity against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria after a simple post-treatment irradiation method with a red laser during a short time period.LAQV@REQUIMTEDQ - Departamento de QuímicaMEtRICS - Centro de Engenharia Mecânica e Sustentabilidade de RecursosDCTB - Departamento de Ciências e Tecnologia da Biomassa (ex-GDEH)RUNFernández-Lodeiro, AdriánDjafari, JamilaFernández-Lodeiro, JavierDuarte, Maria PaulaMauricio, Elisabete MuchagatoCapelo-Martínez, José LuisLodeiro, Carlos2021-12-20T23:17:20Z2021-05-192021-05-19T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/129525eng2079-4991PURE: 33430007https://doi.org/10.3390/nano11051338info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:57:40Zoai:run.unl.pt:10362/129525Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:28:54.564458Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
title Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
spellingShingle Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
Fernández-Lodeiro, Adrián
Antibacterial activity
Gold nanoparticles
Gold nanorod
Mesoporous silica
Methylene blue
Chemical Engineering(all)
Materials Science(all)
title_short Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
title_full Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
title_fullStr Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
title_full_unstemmed Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
title_sort Synthesis of mesoporous silica coated gold nanorods loaded with methylene blue and its potentials in antibacterial applications
author Fernández-Lodeiro, Adrián
author_facet Fernández-Lodeiro, Adrián
Djafari, Jamila
Fernández-Lodeiro, Javier
Duarte, Maria Paula
Mauricio, Elisabete Muchagato
Capelo-Martínez, José Luis
Lodeiro, Carlos
author_role author
author2 Djafari, Jamila
Fernández-Lodeiro, Javier
Duarte, Maria Paula
Mauricio, Elisabete Muchagato
Capelo-Martínez, José Luis
Lodeiro, Carlos
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
MEtRICS - Centro de Engenharia Mecânica e Sustentabilidade de Recursos
DCTB - Departamento de Ciências e Tecnologia da Biomassa (ex-GDEH)
RUN
dc.contributor.author.fl_str_mv Fernández-Lodeiro, Adrián
Djafari, Jamila
Fernández-Lodeiro, Javier
Duarte, Maria Paula
Mauricio, Elisabete Muchagato
Capelo-Martínez, José Luis
Lodeiro, Carlos
dc.subject.por.fl_str_mv Antibacterial activity
Gold nanoparticles
Gold nanorod
Mesoporous silica
Methylene blue
Chemical Engineering(all)
Materials Science(all)
topic Antibacterial activity
Gold nanoparticles
Gold nanorod
Mesoporous silica
Methylene blue
Chemical Engineering(all)
Materials Science(all)
description POCI-01-0145-FEDER—007265 contract under DL57 SFRH/BD/52528/2014
publishDate 2021
dc.date.none.fl_str_mv 2021-12-20T23:17:20Z
2021-05-19
2021-05-19T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/129525
url http://hdl.handle.net/10362/129525
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-4991
PURE: 33430007
https://doi.org/10.3390/nano11051338
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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