Contribution of Alternative Splicing to the ABA Response

• Main Author: Díez, Alba R.
• Publication Date: 2024
• Language: eng
• Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
• Download full: http://hdl.handle.net/10362/183316
• topic: ABA response; splicing; Arabidopsis thaliana; stress responses; Arabidopsis ecotypes; Domínio/Área Científica::Ciências Naturais

"Alternative splicing has emerged as a significant contributor to plant stress tolerance, yet the specific genes and events involved remain largely elusive. The plant hormone abscisic acid (ABA) serves as a key regulator of plant stress responses, orchestrating reactions to both abiotic and biotic stress through its intricate signalling pathway. ABA signalling can trigger rapid responses, such as stomatal closure, and induce longer-term changes in gene expression and post-transcriptional regulation. In particular, alternative splicing is being recognized as an important mechanism in plant stress responses by targeting the ABA pathway. In my PhD project, I used natural variance in the model plant Arabidopsis thaliana to substantiate a role for alternative splicing in stress responses mediated by the ABA phytohormone and to uncover functionally significant splicing targets.(...)"