Virulence factors in coagulase-negative staphylococci

Bibliographic Details
Main Author: França, Ângela Maria Oliveira Sousa
Publication Date: 2021
Other Authors: Gaio, Vânia Silva, Lopes, Nathalie, Melo, Luís Daniel Rodrigues
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/1822/70255
Summary: Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.
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spelling Virulence factors in coagulase-negative staphylococciCoagulase-negative staphylococciBiofilmsVirulence factorsScience & TechnologyCoagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.: V.G. and N.L. acknowledge the FCT fellowship, respectively, SFRH/BD/13145/2017 and SFRH/BD/136998/2018.info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoFrança, Ângela Maria Oliveira SousaGaio, Vânia SilvaLopes, NathalieMelo, Luís Daniel Rodrigues2021-022021-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/70255engFrança, Angela; Gaio, Vania; Lopes, N.; Melo, Luís Daniel Rodrigues, Virulence Factors in Coagulase-Negative Staphylococci. Pathogens, 10(2), 170, 20212076-081710.3390/pathogens10020170https://www.mdpi.com/2076-0817/10/2/170info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T04:18:04Zoai:repositorium.sdum.uminho.pt:1822/70255Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T14:44:49.065050Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Virulence factors in coagulase-negative staphylococci
title Virulence factors in coagulase-negative staphylococci
spellingShingle Virulence factors in coagulase-negative staphylococci
França, Ângela Maria Oliveira Sousa
Coagulase-negative staphylococci
Biofilms
Virulence factors
Science & Technology
title_short Virulence factors in coagulase-negative staphylococci
title_full Virulence factors in coagulase-negative staphylococci
title_fullStr Virulence factors in coagulase-negative staphylococci
title_full_unstemmed Virulence factors in coagulase-negative staphylococci
title_sort Virulence factors in coagulase-negative staphylococci
author França, Ângela Maria Oliveira Sousa
author_facet França, Ângela Maria Oliveira Sousa
Gaio, Vânia Silva
Lopes, Nathalie
Melo, Luís Daniel Rodrigues
author_role author
author2 Gaio, Vânia Silva
Lopes, Nathalie
Melo, Luís Daniel Rodrigues
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv França, Ângela Maria Oliveira Sousa
Gaio, Vânia Silva
Lopes, Nathalie
Melo, Luís Daniel Rodrigues
dc.subject.por.fl_str_mv Coagulase-negative staphylococci
Biofilms
Virulence factors
Science & Technology
topic Coagulase-negative staphylococci
Biofilms
Virulence factors
Science & Technology
description Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.
publishDate 2021
dc.date.none.fl_str_mv 2021-02
2021-02-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/70255
url http://hdl.handle.net/1822/70255
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv França, Angela; Gaio, Vania; Lopes, N.; Melo, Luís Daniel Rodrigues, Virulence Factors in Coagulase-Negative Staphylococci. Pathogens, 10(2), 170, 2021
2076-0817
10.3390/pathogens10020170
https://www.mdpi.com/2076-0817/10/2/170
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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