The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs

Bibliographic Details
Main Author: Santana, Isabel
Publication Date: 2015
Other Authors: Farinha, Filipa, Freitas, Sandra, Rodrigues, Vítor, Carvalho, Álvaro
Format: Article
Language: por
eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025
Summary: Introduction: The incidence and prevalence of global dementia and Alzheimer’s disease (AD) increase with age, almost doubling every five years after the sixth decade of life. Demographic aging is a reality in Portugal, being expectable that the number of dementia cases also increases. Even so, dementia-epidemiological data in Portugal is scarce and cost-of-illness studies are almost inexistent. Our aims were to obtain up-to-date information about the prevalence of dementia/ Alzheimer’s disease in Portugal, to estimate thenumber of cases effectively diagnosed as Alzheimer’s disease and to determine illness-costs with specific dementia treatment.Material and Methods: The numbers of age-adjusted prevalence of dementia obtained for Occidental Europe (Alzheimer’s Disease International study), where applied to the resident population in Portugal (2013). Estimations related to diagnosis and treatment-costs were based in data provided by the Intercontinental Marketing Services Health (IMSH) – 2013.Results: The estimated number of Portuguese people with dementia among those aged ≥ 60 years, is 160287, representing 5.91% of this population-stratum. Knowing Alzheimer’s disease is responsible for 50-70% of all cases, we might conclude there are between 80144 and 112201 patients. According to IMSH-data, 76250 receive anti-dementia drugs and the costs of this kind of medication is 37 M€/year.Conclusions: As a consequence of the demographic aging, also the number of dementia cases increases. Aparentely, not all Alzheimer’s disease patients receive the recommended medication, suggesting this condition is still under-diagnosed. However, figures indicate a positive progression with an increment of treated cases and a reduction of medication-costs.
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spelling The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-CostsEpidemiologia da Demência e da Doença de Alzheimer em Portugal: Estimativas da Prevalência e dos Encargos Financeiros com a MedicaçãoAlzheimer DiseaseCost of IllnessDementiaPortugalPrevalence.Custos do TratamentoDemênciaDoença de AlzheimerPortugalPrevalência.Introduction: The incidence and prevalence of global dementia and Alzheimer’s disease (AD) increase with age, almost doubling every five years after the sixth decade of life. Demographic aging is a reality in Portugal, being expectable that the number of dementia cases also increases. Even so, dementia-epidemiological data in Portugal is scarce and cost-of-illness studies are almost inexistent. Our aims were to obtain up-to-date information about the prevalence of dementia/ Alzheimer’s disease in Portugal, to estimate thenumber of cases effectively diagnosed as Alzheimer’s disease and to determine illness-costs with specific dementia treatment.Material and Methods: The numbers of age-adjusted prevalence of dementia obtained for Occidental Europe (Alzheimer’s Disease International study), where applied to the resident population in Portugal (2013). Estimations related to diagnosis and treatment-costs were based in data provided by the Intercontinental Marketing Services Health (IMSH) – 2013.Results: The estimated number of Portuguese people with dementia among those aged ≥ 60 years, is 160287, representing 5.91% of this population-stratum. Knowing Alzheimer’s disease is responsible for 50-70% of all cases, we might conclude there are between 80144 and 112201 patients. According to IMSH-data, 76250 receive anti-dementia drugs and the costs of this kind of medication is 37 M€/year.Conclusions: As a consequence of the demographic aging, also the number of dementia cases increases. Aparentely, not all Alzheimer’s disease patients receive the recommended medication, suggesting this condition is still under-diagnosed. However, figures indicate a positive progression with an increment of treated cases and a reduction of medication-costs.Introdução: A incidência e prevalência de demência e de Doença de Alzheimer aumentam com a idade, duplicando a cada cinco anos após a sexta década de vida. Portugal é um país envelhecido, previsivelmente com um número crescente de casos de demência. No entanto, os dados epidemiológicos são escassos e os estudos sobre os custos da doença praticamente inexistentes. Propomo-nos apresentar uma estimativa actualizada da prevalência de demência/ Doença de Alzheimer em Portugal e inferir, a partir da prescrição específica para demência, o número de diagnósticos efectivos e os encargos financeiros com esses medicamentos.Material e Métodos: À população residente em Portugal (2013), aplicámos os valores de prevalência de demência para a Europa Ocidental (estudo da Alzheimer’s Disease International). A estimativa dos diagnósticos efectivos de Doença de Alzheimer e dos encargos financeiros com medicação específica baseou-se nas informações do Intercontinental Marketing Services Health (IMSH) – 2013.Resultados: O número estimado de Portugueses com mais de 60 anos e com demência foi 160287, o que corresponde a 5,91% deste universo populacional. Sabendo que a Doença de Alzheimer representa 50-70% dos casos, inferimos que existirão entre 80144 e 112201 doentes. Por outro lado, os dados da IMSH indicam que estarão diagnosticados e a receceber anti-demenciais 76250 doentes, representando um encargo financeiro de 37 M€/ano.Conclusão: O envelhecimento da população incrementa o número de casos de demência. Aparentemente, nem todos os doentes com Doença de Alzheimer recebem a medicação aconselhada, sugerindo que esta condição ainda está sub-diagnosticada. A evolução tem sido positiva, com incremento do número de doentes tratados e redução dos custos com fármacos específicos.Ordem dos Médicos2015-03-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/mswordapplication/mswordapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025oai:ojs.www.actamedicaportuguesa.com:article/6025Acta Médica Portuguesa; Vol. 28 No. 2 (2015): March-April; 182-188Acta Médica Portuguesa; Vol. 28 N.º 2 (2015): Março-Abril; 182-1881646-07580870-399Xreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/4295https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/4442https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/7594https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/7662https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/7663https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/7664https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/7665https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/7666https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6025/7667Santana, IsabelFarinha, FilipaFreitas, SandraRodrigues, VítorCarvalho, Álvaroinfo:eu-repo/semantics/openAccess2022-12-20T11:04:41Zoai:ojs.www.actamedicaportuguesa.com:article/6025Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T10:40:12.986618Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
Epidemiologia da Demência e da Doença de Alzheimer em Portugal: Estimativas da Prevalência e dos Encargos Financeiros com a Medicação
title The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
spellingShingle The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
Santana, Isabel
Alzheimer Disease
Cost of Illness
Dementia
Portugal
Prevalence.
Custos do Tratamento
Demência
Doença de Alzheimer
Portugal
Prevalência.
title_short The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
title_full The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
title_fullStr The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
title_full_unstemmed The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
title_sort The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs
author Santana, Isabel
author_facet Santana, Isabel
Farinha, Filipa
Freitas, Sandra
Rodrigues, Vítor
Carvalho, Álvaro
author_role author
author2 Farinha, Filipa
Freitas, Sandra
Rodrigues, Vítor
Carvalho, Álvaro
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santana, Isabel
Farinha, Filipa
Freitas, Sandra
Rodrigues, Vítor
Carvalho, Álvaro
dc.subject.por.fl_str_mv Alzheimer Disease
Cost of Illness
Dementia
Portugal
Prevalence.
Custos do Tratamento
Demência
Doença de Alzheimer
Portugal
Prevalência.
topic Alzheimer Disease
Cost of Illness
Dementia
Portugal
Prevalence.
Custos do Tratamento
Demência
Doença de Alzheimer
Portugal
Prevalência.
description Introduction: The incidence and prevalence of global dementia and Alzheimer’s disease (AD) increase with age, almost doubling every five years after the sixth decade of life. Demographic aging is a reality in Portugal, being expectable that the number of dementia cases also increases. Even so, dementia-epidemiological data in Portugal is scarce and cost-of-illness studies are almost inexistent. Our aims were to obtain up-to-date information about the prevalence of dementia/ Alzheimer’s disease in Portugal, to estimate thenumber of cases effectively diagnosed as Alzheimer’s disease and to determine illness-costs with specific dementia treatment.Material and Methods: The numbers of age-adjusted prevalence of dementia obtained for Occidental Europe (Alzheimer’s Disease International study), where applied to the resident population in Portugal (2013). Estimations related to diagnosis and treatment-costs were based in data provided by the Intercontinental Marketing Services Health (IMSH) – 2013.Results: The estimated number of Portuguese people with dementia among those aged ≥ 60 years, is 160287, representing 5.91% of this population-stratum. Knowing Alzheimer’s disease is responsible for 50-70% of all cases, we might conclude there are between 80144 and 112201 patients. According to IMSH-data, 76250 receive anti-dementia drugs and the costs of this kind of medication is 37 M€/year.Conclusions: As a consequence of the demographic aging, also the number of dementia cases increases. Aparentely, not all Alzheimer’s disease patients receive the recommended medication, suggesting this condition is still under-diagnosed. However, figures indicate a positive progression with an increment of treated cases and a reduction of medication-costs.
publishDate 2015
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 28 No. 2 (2015): March-April; 182-188
Acta Médica Portuguesa; Vol. 28 N.º 2 (2015): Março-Abril; 182-188
1646-0758
0870-399X
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