Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates

Bibliographic Details
Main Author: Fernandes, Maria J. G.
Publication Date: 2007
Other Authors: Gonçalves, M. Sameiro T., Costa, Susana P. G.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://hdl.handle.net/1822/86457
Summary: The linkage of model neurotransmitter L-amino acids, such as glycine, alanine, beta-alanine, glutamic acid and gamma-aminobutyric acid, to a pyrenylmethyl group as the fluorescent moiety through an ester bond at their carboxylic functions at the main and side chains (in the case of glutamic acid) was investigated. The behaviour of the resulting fluorescent conjugates towards photocleavage was studied in different cleavage conditions, namely the wavelength of irradiation and the use of different solvents, in a photochemical reactor equipped with lamps of 254, 300, 350 and 419 nm, followed by HPLC/UV monitoring. (C) 2007 Elsevier Ltd. All rights reserved.
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spelling Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugatesamino acid neurotransmitterspyrenefluorescent conjugatesphotocleavable protecting groupsphotoreleaseCiências Naturais::Ciências QuímicasScience & TechnologyThe linkage of model neurotransmitter L-amino acids, such as glycine, alanine, beta-alanine, glutamic acid and gamma-aminobutyric acid, to a pyrenylmethyl group as the fluorescent moiety through an ester bond at their carboxylic functions at the main and side chains (in the case of glutamic acid) was investigated. The behaviour of the resulting fluorescent conjugates towards photocleavage was studied in different cleavage conditions, namely the wavelength of irradiation and the use of different solvents, in a photochemical reactor equipped with lamps of 254, 300, 350 and 419 nm, followed by HPLC/UV monitoring. (C) 2007 Elsevier Ltd. All rights reserved.- Fundação para a Ciência e a Tecnologia(undefined)Pergamon-Elsevier Science LtdUniversidade do MinhoFernandes, Maria J. G.Gonçalves, M. Sameiro T.Costa, Susana P. G.20072007-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/86457engFernandes, M. J. G., Gonçalves, M. S. T., & Costa, S. P. G. (2007, October). Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates. Tetrahedron. Elsevier BV. http://doi.org/10.1016/j.tet.2007.07.1070040-402010.1016/j.tet.2007.07.107https://www.sciencedirect.com/science/article/pii/S0040402007013804info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T05:22:15Zoai:repositorium.sdum.uminho.pt:1822/86457Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:16:11.059152Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
title Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
spellingShingle Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
Fernandes, Maria J. G.
amino acid neurotransmitters
pyrene
fluorescent conjugates
photocleavable protecting groups
photorelease
Ciências Naturais::Ciências Químicas
Science & Technology
title_short Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
title_full Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
title_fullStr Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
title_full_unstemmed Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
title_sort Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates
author Fernandes, Maria J. G.
author_facet Fernandes, Maria J. G.
Gonçalves, M. Sameiro T.
Costa, Susana P. G.
author_role author
author2 Gonçalves, M. Sameiro T.
Costa, Susana P. G.
author2_role author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Fernandes, Maria J. G.
Gonçalves, M. Sameiro T.
Costa, Susana P. G.
dc.subject.por.fl_str_mv amino acid neurotransmitters
pyrene
fluorescent conjugates
photocleavable protecting groups
photorelease
Ciências Naturais::Ciências Químicas
Science & Technology
topic amino acid neurotransmitters
pyrene
fluorescent conjugates
photocleavable protecting groups
photorelease
Ciências Naturais::Ciências Químicas
Science & Technology
description The linkage of model neurotransmitter L-amino acids, such as glycine, alanine, beta-alanine, glutamic acid and gamma-aminobutyric acid, to a pyrenylmethyl group as the fluorescent moiety through an ester bond at their carboxylic functions at the main and side chains (in the case of glutamic acid) was investigated. The behaviour of the resulting fluorescent conjugates towards photocleavage was studied in different cleavage conditions, namely the wavelength of irradiation and the use of different solvents, in a photochemical reactor equipped with lamps of 254, 300, 350 and 419 nm, followed by HPLC/UV monitoring. (C) 2007 Elsevier Ltd. All rights reserved.
publishDate 2007
dc.date.none.fl_str_mv 2007
2007-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/86457
url https://hdl.handle.net/1822/86457
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Fernandes, M. J. G., Gonçalves, M. S. T., & Costa, S. P. G. (2007, October). Photorelease of amino acid neurotransmitters from pyrenylmethyl ester conjugates. Tetrahedron. Elsevier BV. http://doi.org/10.1016/j.tet.2007.07.107
0040-4020
10.1016/j.tet.2007.07.107
https://www.sciencedirect.com/science/article/pii/S0040402007013804
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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