The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study

• Main Author: Jiskoot, Lize C.
• Publication Date: 2023
• Other Authors: Russell, Lucy L., Peakman, Georgia, Convery, Rhian S., Greaves, Caroline V., Bocchetta, Martina, Poos, Jackie M., Seelaar, Harro, Giannini, Lucia A. A., van Swieten, John C., van Minkelen, Rick, Pijnenburg, Yolande A. L., Rowe, James B., Borroni, Barbara, Galimberti, Daniela, Masellis, Mario, Tartaglia, Carmela, Finger, Elizabeth, Butler, Chris R., Graff, Caroline, Laforce, Robert, Sánchez-Valle, Raquel, de Mendonça, Alexandre, Moreno, Fermin, Synofzik, Matthis, Vandenberghe, Rik, Ducharme, Simon, le Ber, Isabelle, Levin, Johannes, Otto, Markus, Pasquier, Florence, Santana, Isabel, Cash, David M., Thomas, David, Rohrer, Jonathan D.
• Format: Article
• Language: eng
• Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
• Download full: https://hdl.handle.net/10316/113732; https://doi.org/10.1016/j.jns.2023.120590
• topic: Frontotemporal dementia; Cognition; Neuropsychology; Genetic; Presymptomatic; Marker; Humans; C9orf72 Protein; Cross-Sectional Studies; Neuropsychological Tests; Atrophy; Mutation; tau Proteins; Frontotemporal Dementia

Sensitive cognitive markers are still needed for frontotemporal dementia (FTD). The Benson Complex Figure Test (BCFT) is an interesting candidate test, as it assesses visuospatial, visual memory, and executive abilities, allowing the detection of multiple mechanisms of cognitive impairment. To investigate differences in BCFT Copy, Recall and Recognition in presymptomatic and symptomatic FTD mutation carriers, and to explore its cognitive and neuroimaging correlates.