Efficacy of peritoneal dialysis in patients with refractory congestive heart failure

Bibliographic Details
Main Author: Timóteo, Ana Teresa
Publication Date: 2023
Other Authors: Mano, Tânia Branco
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/149280
Summary: Funding: Open access funding provided by FCT|FCCN (b-on).
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spelling Efficacy of peritoneal dialysis in patients with refractory congestive heart failurea systematic review and meta-analysisCongestive heart failurePeritoneal dialysisRefractoryCardiology and Cardiovascular MedicineFunding: Open access funding provided by FCT|FCCN (b-on).Refractory congestive heart failure (RCHF) is a common complication in the natural history of advanced heart failure. Peritoneal dialysis (PD) is a possible alternative in those patients, but studies are scarce, and mostly with small samples. We conducted this meta-analysis to evaluate the effects of PD in patients with RCHF. Articles published before July 2020 in the following databases: PubMed, Web of Science, and CENTRAL. Mean differences (MD) and 95% confidence intervals (CIs) were computed to generate a pooled effect size with a random effects model. We also assessed heterogeneity, risk of bias, publication bias, and quality of evidence. Twenty observational studies (n = 769) were included, with a “before and after intervention” design. PD was associated with a significant reduction in NYHA functional class (MD −1.37, 95% CI −0.78 to −1.96) and length of hospitalisation (MD −34.8, 95% CI −20.6 to −48.9 days/patient/year), a small but significant increase in left ventricular ejection fraction (MD 4.3, 95%CI 1.9 to 6.8%) and a non-significant change in glomerular filtration rate (MD −3.0, 95% CI −6.0 to 0 mL/min/1.73m2). Heterogeneity among studies was significant and overall risk of bias was rated from moderate to critical. No significant publication bias was found, and the overall quality of evidence was very low for all outcomes. PD in patients with RCHF improved functional class, length of hospitalisation, and ventricular functional, and had no impact in renal function. Further randomised clinical trials are warranted to confirm our results that showed some limitations.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNTimóteo, Ana TeresaMano, Tânia Branco2023-02-15T22:20:47Z2023-092023-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/149280eng1382-4147PURE: 53066303https://doi.org/10.1007/s10741-023-10297-3info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:09:14Zoai:run.unl.pt:10362/149280Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:39:45.290656Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
a systematic review and meta-analysis
title Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
spellingShingle Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
Timóteo, Ana Teresa
Congestive heart failure
Peritoneal dialysis
Refractory
Cardiology and Cardiovascular Medicine
title_short Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
title_full Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
title_fullStr Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
title_full_unstemmed Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
title_sort Efficacy of peritoneal dialysis in patients with refractory congestive heart failure
author Timóteo, Ana Teresa
author_facet Timóteo, Ana Teresa
Mano, Tânia Branco
author_role author
author2 Mano, Tânia Branco
author2_role author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Timóteo, Ana Teresa
Mano, Tânia Branco
dc.subject.por.fl_str_mv Congestive heart failure
Peritoneal dialysis
Refractory
Cardiology and Cardiovascular Medicine
topic Congestive heart failure
Peritoneal dialysis
Refractory
Cardiology and Cardiovascular Medicine
description Funding: Open access funding provided by FCT|FCCN (b-on).
publishDate 2023
dc.date.none.fl_str_mv 2023-02-15T22:20:47Z
2023-09
2023-09-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/149280
url http://hdl.handle.net/10362/149280
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1382-4147
PURE: 53066303
https://doi.org/10.1007/s10741-023-10297-3
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833596870147964928

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