The role of Spongia Sp. In the discovery of marine lead compounds

Detalhes bibliográficos
Autor(a) principal: Maximo, P.
Data de Publicação: 2016
Outros Autores: Ferreira, Luísa M., Branco, Paula, Lima, Pedro, Lourenço, Ana
Tipo de documento: Outros
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://doi.org/10.3390/md14080139
Resumo: Promar (31-04-01-FEP-308); QREN (2014/39985)
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spelling The role of Spongia Sp. In the discovery of marine lead compoundsBiological activityC21 furanoterpenesDiterpenesMacrolidesSesquiterpene quinonesSesterterpenesSpongia sp.SterolsDrug DiscoverySDG 14 - Life Below WaterPromar (31-04-01-FEP-308); QREN (2014/39985)A comprehensive review on the chemistry of Spongia sp. is here presented, together with the biological activity of the isolated compounds. The compounds are grouped in sesquiterpene quinones, diterpenes, C21 and other linear furanoterpenes, sesterterpenes, sterols (including secosterols), macrolides and miscellaneous compounds. Among other reports we include studies on the intraspecific diversity of a Mediterranean species, compounds isolated from associated sponge and nudibranch and compounds isolated from S. zimocca and the red seaweed Laurentia microcladia. Under biological activity a table of the reported biological activities of the various compounds and the biological screening of extracts are described. The present review covers the literature from 1971 to 2015.LAQV@REQUIMTEDQ - Departamento de QuímicaNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNMaximo, P.Ferreira, Luísa M.Branco, PaulaLima, PedroLourenço, Ana2017-05-27T00:01:10Z2016-08-012016-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://doi.org/10.3390/md14080139engPURE: 1122256http://www.scopus.com/inward/record.url?scp=84984998279&partnerID=8YFLogxKhttps://doi.org/10.3390/md14080139info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:25:36Zoai:run.unl.pt:10362/20785Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T16:56:42.254080Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv The role of Spongia Sp. In the discovery of marine lead compounds
title The role of Spongia Sp. In the discovery of marine lead compounds
spellingShingle The role of Spongia Sp. In the discovery of marine lead compounds
Maximo, P.
Biological activity
C21 furanoterpenes
Diterpenes
Macrolides
Sesquiterpene quinones
Sesterterpenes
Spongia sp.
Sterols
Drug Discovery
SDG 14 - Life Below Water
title_short The role of Spongia Sp. In the discovery of marine lead compounds
title_full The role of Spongia Sp. In the discovery of marine lead compounds
title_fullStr The role of Spongia Sp. In the discovery of marine lead compounds
title_full_unstemmed The role of Spongia Sp. In the discovery of marine lead compounds
title_sort The role of Spongia Sp. In the discovery of marine lead compounds
author Maximo, P.
author_facet Maximo, P.
Ferreira, Luísa M.
Branco, Paula
Lima, Pedro
Lourenço, Ana
author_role author
author2 Ferreira, Luísa M.
Branco, Paula
Lima, Pedro
Lourenço, Ana
author2_role author
author
author
author
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Maximo, P.
Ferreira, Luísa M.
Branco, Paula
Lima, Pedro
Lourenço, Ana
dc.subject.por.fl_str_mv Biological activity
C21 furanoterpenes
Diterpenes
Macrolides
Sesquiterpene quinones
Sesterterpenes
Spongia sp.
Sterols
Drug Discovery
SDG 14 - Life Below Water
topic Biological activity
C21 furanoterpenes
Diterpenes
Macrolides
Sesquiterpene quinones
Sesterterpenes
Spongia sp.
Sterols
Drug Discovery
SDG 14 - Life Below Water
description Promar (31-04-01-FEP-308); QREN (2014/39985)
publishDate 2016
dc.date.none.fl_str_mv 2016-08-01
2016-08-01T00:00:00Z
2017-05-27T00:01:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/other
format other
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.3390/md14080139
url https://doi.org/10.3390/md14080139
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv PURE: 1122256
http://www.scopus.com/inward/record.url?scp=84984998279&partnerID=8YFLogxK
https://doi.org/10.3390/md14080139
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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