Role of DNA methylation in persistent diabetic macular edema

Bibliographic Details
Main Author: Camacho, Pedro
Publication Date: 2022
Other Authors: Pereira, Bruno, Ribeiro, Edna, Varandas, Teresa, Henriques, José, Nascimento, João, Dutra-Medeiros, Marco, Silva, Carina, Delgadinho, Mariana, Oliveira, Ketlyn, Brito, Miguel
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.21/16420
Summary: Background: a) Disease duration and metabolic control are insufficient to understand Diabetic Macular Edema (DME), the leading cause of vision loss in people with diabetes; b) 30-40% of cases of DME do not respond optimally to AVEGF (loading phase); c) poor genetic association in DR development (<25% RD) and PDR progression (25-50%). Purpose: To study the role of DNA methyltransferase expression (DNMT1,DNMT3a, DNMT3b) in persistent diabetic macular edema.
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spelling Role of DNA methylation in persistent diabetic macular edemaOphthalmologyPersistent diabetic macular edemaDNA methylationIPL/2021/DiffMeDiME_ESTeSLBackground: a) Disease duration and metabolic control are insufficient to understand Diabetic Macular Edema (DME), the leading cause of vision loss in people with diabetes; b) 30-40% of cases of DME do not respond optimally to AVEGF (loading phase); c) poor genetic association in DR development (<25% RD) and PDR progression (25-50%). Purpose: To study the role of DNA methyltransferase expression (DNMT1,DNMT3a, DNMT3b) in persistent diabetic macular edema.RCIPLCamacho, PedroPereira, BrunoRibeiro, EdnaVarandas, TeresaHenriques, JoséNascimento, JoãoDutra-Medeiros, MarcoSilva, CarinaDelgadinho, MarianaOliveira, KetlynBrito, Miguel2023-08-28T12:07:02Z2022-092022-09-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.21/16420enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-12T09:31:04Zoai:repositorio.ipl.pt:10400.21/16420Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T20:01:20.655216Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Role of DNA methylation in persistent diabetic macular edema
title Role of DNA methylation in persistent diabetic macular edema
spellingShingle Role of DNA methylation in persistent diabetic macular edema
Camacho, Pedro
Ophthalmology
Persistent diabetic macular edema
DNA methylation
IPL/2021/DiffMeDiME_ESTeSL
title_short Role of DNA methylation in persistent diabetic macular edema
title_full Role of DNA methylation in persistent diabetic macular edema
title_fullStr Role of DNA methylation in persistent diabetic macular edema
title_full_unstemmed Role of DNA methylation in persistent diabetic macular edema
title_sort Role of DNA methylation in persistent diabetic macular edema
author Camacho, Pedro
author_facet Camacho, Pedro
Pereira, Bruno
Ribeiro, Edna
Varandas, Teresa
Henriques, José
Nascimento, João
Dutra-Medeiros, Marco
Silva, Carina
Delgadinho, Mariana
Oliveira, Ketlyn
Brito, Miguel
author_role author
author2 Pereira, Bruno
Ribeiro, Edna
Varandas, Teresa
Henriques, José
Nascimento, João
Dutra-Medeiros, Marco
Silva, Carina
Delgadinho, Mariana
Oliveira, Ketlyn
Brito, Miguel
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Camacho, Pedro
Pereira, Bruno
Ribeiro, Edna
Varandas, Teresa
Henriques, José
Nascimento, João
Dutra-Medeiros, Marco
Silva, Carina
Delgadinho, Mariana
Oliveira, Ketlyn
Brito, Miguel
dc.subject.por.fl_str_mv Ophthalmology
Persistent diabetic macular edema
DNA methylation
IPL/2021/DiffMeDiME_ESTeSL
topic Ophthalmology
Persistent diabetic macular edema
DNA methylation
IPL/2021/DiffMeDiME_ESTeSL
description Background: a) Disease duration and metabolic control are insufficient to understand Diabetic Macular Edema (DME), the leading cause of vision loss in people with diabetes; b) 30-40% of cases of DME do not respond optimally to AVEGF (loading phase); c) poor genetic association in DR development (<25% RD) and PDR progression (25-50%). Purpose: To study the role of DNA methyltransferase expression (DNMT1,DNMT3a, DNMT3b) in persistent diabetic macular edema.
publishDate 2022
dc.date.none.fl_str_mv 2022-09
2022-09-01T00:00:00Z
2023-08-28T12:07:02Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/16420
url http://hdl.handle.net/10400.21/16420
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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