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Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)

Bibliographic Details
Main Author: Rocha, João Victor
Publication Date: 2022
Other Authors: Marques, Ana Patricia, MacEdo, Antonio Filipe, Afonso-Silva, Marta, Laires, Pedro, Almeida, Ana Sofia, Fernandes, Julieta, Pardal, Marisa, Santana, Rui
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/137520
Summary: Funding Information: Funding This analysis was funded by Novartis Farma, Produtos Farmacêuticos SA (no grant number). Publisher Copyright: © 2022 Georg Thieme Verlag. All rights reserved.
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spelling Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)a retrospective analysis of administrative datamedical retinaophthalmologypublic healthMedicine(all)SDG 3 - Good Health and Well-beingFunding Information: Funding This analysis was funded by Novartis Farma, Produtos Farmacêuticos SA (no grant number). Publisher Copyright: © 2022 Georg Thieme Verlag. All rights reserved.Aims The arrival of anti-vascular endothelial growth factor (anti-VEGF) therapies represented a treatment shift for several ophthalmological disorders and led to an increasing number of patients undergoing intravitreal injections. The aims of this observational study were to assess the expansion of anti-VEGF intravitreal injections in the Portuguese National Health System (NHS) and to identify factors correlated with geographical variations in episode rates. Methods Administrative database on discharge from Portuguese NHS hospitals was analysed for annual values and rates of intravitreal anti-VEGF injections at a national and regional level, between 2013 and 2018. Results The number of episodes of anti-VEGF treatment and patients treated increased 16% and 9% per year, respectively, between 2013 and 2018. During the study period around 72% of patients were treated in the Metropolitan areas of Lisbon and Porto and in the Central region. Intravitreal anti-VEGF treatment rates in 2018 were 560 per 100 000 population and presented high variability between municipalities. Higher anti-VEGF treatment rates at the municipality level were associated with shorter distances between their residence and the hospital. At the hospital level, higher ratio of ophthalmologists and higher organisational level were associated with higher anti-VEGF treatment rates. Conclusion The number of episodes and patients treated with anti-VEGF injections has been growing in recent years. Proximity to healthcare, more access to ophthalmologists and hospitals with higher organisational levels are associated with higher anti-VEGF treatment rates. Improving access is crucial to reduce regional discrepancies and ensure optimal treatment frequency, which may improve health outcomes.Comprehensive Health Research Centre (CHRC) - Pólo ENSPCentro de Investigação em Saúde Pública (CISP/PHRC)Escola Nacional de Saúde Pública (ENSP)RUNRocha, João VictorMarques, Ana PatriciaMacEdo, Antonio FilipeAfonso-Silva, MartaLaires, PedroAlmeida, Ana SofiaFernandes, JulietaPardal, MarisaSantana, Rui2022-05-06T22:34:24Z2022-04-062022-04-06T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/137520eng2044-6055PURE: 43728999https://doi.org/10.1136/bmjopen-2021-055478info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:01:21Zoai:run.unl.pt:10362/137520Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:32:18.491156Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
a retrospective analysis of administrative data
title Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
spellingShingle Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
Rocha, João Victor
medical retina
ophthalmology
public health
Medicine(all)
SDG 3 - Good Health and Well-being
title_short Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
title_full Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
title_fullStr Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
title_full_unstemmed Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
title_sort Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013-2018)
author Rocha, João Victor
author_facet Rocha, João Victor
Marques, Ana Patricia
MacEdo, Antonio Filipe
Afonso-Silva, Marta
Laires, Pedro
Almeida, Ana Sofia
Fernandes, Julieta
Pardal, Marisa
Santana, Rui
author_role author
author2 Marques, Ana Patricia
MacEdo, Antonio Filipe
Afonso-Silva, Marta
Laires, Pedro
Almeida, Ana Sofia
Fernandes, Julieta
Pardal, Marisa
Santana, Rui
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Centro de Investigação em Saúde Pública (CISP/PHRC)
Escola Nacional de Saúde Pública (ENSP)
RUN
dc.contributor.author.fl_str_mv Rocha, João Victor
Marques, Ana Patricia
MacEdo, Antonio Filipe
Afonso-Silva, Marta
Laires, Pedro
Almeida, Ana Sofia
Fernandes, Julieta
Pardal, Marisa
Santana, Rui
dc.subject.por.fl_str_mv medical retina
ophthalmology
public health
Medicine(all)
SDG 3 - Good Health and Well-being
topic medical retina
ophthalmology
public health
Medicine(all)
SDG 3 - Good Health and Well-being
description Funding Information: Funding This analysis was funded by Novartis Farma, Produtos Farmacêuticos SA (no grant number). Publisher Copyright: © 2022 Georg Thieme Verlag. All rights reserved.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-06T22:34:24Z
2022-04-06
2022-04-06T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/137520
url http://hdl.handle.net/10362/137520
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2044-6055
PURE: 43728999
https://doi.org/10.1136/bmjopen-2021-055478
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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