Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography

Detalhes bibliográficos
Autor(a) principal: Arafah, Rami
Data de Publicação: 2021
Outros Autores: Ribeiro, António E., Rodrigues, Alírio, Pais, Luís S.
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10198/26837
Resumo: The separation and purification of high added value products by liquid chromatography is a very popular technique. The development of more stable and efficient stationary phases, together with the design of innovative and more flexible separation processes, enhanced the use of chromatographic processes, particularly at preparative and industrial scales through fixedbed and simulated moving bed (SMB) technologies. Fixed-bed and SMB techniques are more and more used in the separation of a wide range of products for the pharmaceutical, fine chemistry, biotechnology and food industries. In this context, one of the actual main challenges concerns the design and optimization of these chromatographic processes for challenging multicomponent separations. This includes the development of new and innovative chromatographic processes, combining different design strategies and modes of operation, with different types of stationary and mobile phases.
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spelling Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatographySMBChromatographyNadalolStereoisomersResearch Subject Categories::TECHNOLOGYThe separation and purification of high added value products by liquid chromatography is a very popular technique. The development of more stable and efficient stationary phases, together with the design of innovative and more flexible separation processes, enhanced the use of chromatographic processes, particularly at preparative and industrial scales through fixedbed and simulated moving bed (SMB) technologies. Fixed-bed and SMB techniques are more and more used in the separation of a wide range of products for the pharmaceutical, fine chemistry, biotechnology and food industries. In this context, one of the actual main challenges concerns the design and optimization of these chromatographic processes for challenging multicomponent separations. This includes the development of new and innovative chromatographic processes, combining different design strategies and modes of operation, with different types of stationary and mobile phases.FEUP EdiçõesBiblioteca Digital do IPBArafah, RamiRibeiro, António E.Rodrigues, AlírioPais, Luís S.2023-02-08T15:52:18Z20212021-01-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10198/26837engArafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S. (2022). Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography. In 4th Symposium on Chemical and Biological Engineering. Portoinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-25T12:17:47Zoai:bibliotecadigital.ipb.pt:10198/26837Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T11:45:33.281012Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
title Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
spellingShingle Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
Arafah, Rami
SMB
Chromatography
Nadalol
Stereoisomers
Research Subject Categories::TECHNOLOGY
title_short Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
title_full Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
title_fullStr Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
title_full_unstemmed Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
title_sort Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography
author Arafah, Rami
author_facet Arafah, Rami
Ribeiro, António E.
Rodrigues, Alírio
Pais, Luís S.
author_role author
author2 Ribeiro, António E.
Rodrigues, Alírio
Pais, Luís S.
author2_role author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Arafah, Rami
Ribeiro, António E.
Rodrigues, Alírio
Pais, Luís S.
dc.subject.por.fl_str_mv SMB
Chromatography
Nadalol
Stereoisomers
Research Subject Categories::TECHNOLOGY
topic SMB
Chromatography
Nadalol
Stereoisomers
Research Subject Categories::TECHNOLOGY
description The separation and purification of high added value products by liquid chromatography is a very popular technique. The development of more stable and efficient stationary phases, together with the design of innovative and more flexible separation processes, enhanced the use of chromatographic processes, particularly at preparative and industrial scales through fixedbed and simulated moving bed (SMB) technologies. Fixed-bed and SMB techniques are more and more used in the separation of a wide range of products for the pharmaceutical, fine chemistry, biotechnology and food industries. In this context, one of the actual main challenges concerns the design and optimization of these chromatographic processes for challenging multicomponent separations. This includes the development of new and innovative chromatographic processes, combining different design strategies and modes of operation, with different types of stationary and mobile phases.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01T00:00:00Z
2023-02-08T15:52:18Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/26837
url http://hdl.handle.net/10198/26837
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S. (2022). Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography. In 4th Symposium on Chemical and Biological Engineering. Porto
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv FEUP Edições
publisher.none.fl_str_mv FEUP Edições
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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