Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications

Detalhes bibliográficos
Autor(a) principal: Zielińska, Aleksandra
Data de Publicação: 2021
Outros Autores: Szalata, Marlena, Gorczyński, Adam, Karczewski, Jacek, Eder, Piotr, Severino, Patrícia, Cabeda, José M., Souto, Eliana B., Słomski, Ryszard
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://hdl.handle.net/10316/103810
https://doi.org/10.3390/cancers13081896
Resumo: Physicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals' potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.
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spelling Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applicationsnanoparticlescancer diagnosistreatment of cancernanotherapeuticstherapeutic nanoparticlesPhysicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals' potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.MDPI2021-04-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://hdl.handle.net/10316/103810https://hdl.handle.net/10316/103810https://doi.org/10.3390/cancers13081896eng2072-6694Zielińska, AleksandraSzalata, MarlenaGorczyński, AdamKarczewski, JacekEder, PiotrSeverino, PatríciaCabeda, José M.Souto, Eliana B.Słomski, Ryszardinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2023-01-24T11:05:01Zoai:estudogeral.uc.pt:10316/103810Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T05:53:42.121110Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
title Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
spellingShingle Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
Zielińska, Aleksandra
nanoparticles
cancer diagnosis
treatment of cancer
nanotherapeutics
therapeutic nanoparticles
title_short Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
title_full Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
title_fullStr Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
title_full_unstemmed Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
title_sort Cancer Nanopharmaceuticals: Physicochemical Characterization and In Vitro/In Vivo Applications
author Zielińska, Aleksandra
author_facet Zielińska, Aleksandra
Szalata, Marlena
Gorczyński, Adam
Karczewski, Jacek
Eder, Piotr
Severino, Patrícia
Cabeda, José M.
Souto, Eliana B.
Słomski, Ryszard
author_role author
author2 Szalata, Marlena
Gorczyński, Adam
Karczewski, Jacek
Eder, Piotr
Severino, Patrícia
Cabeda, José M.
Souto, Eliana B.
Słomski, Ryszard
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Zielińska, Aleksandra
Szalata, Marlena
Gorczyński, Adam
Karczewski, Jacek
Eder, Piotr
Severino, Patrícia
Cabeda, José M.
Souto, Eliana B.
Słomski, Ryszard
dc.subject.por.fl_str_mv nanoparticles
cancer diagnosis
treatment of cancer
nanotherapeutics
therapeutic nanoparticles
topic nanoparticles
cancer diagnosis
treatment of cancer
nanotherapeutics
therapeutic nanoparticles
description Physicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals' potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.
publishDate 2021
dc.date.none.fl_str_mv 2021-04-15
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10316/103810
https://hdl.handle.net/10316/103810
https://doi.org/10.3390/cancers13081896
url https://hdl.handle.net/10316/103810
https://doi.org/10.3390/cancers13081896
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2072-6694
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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