Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems

Bibliographic Details
Main Author: Klein, Jaroslav
Publication Date: 2003
Other Authors: Vicente, A. A., Teixeira, J. A.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/1822/1692
Summary: The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yeast biomass at different loadings up to 21 % (v/v) were used in order to mimic the solid phase of conventional high cell density systems. The main hydrodynamic parameters – liquid circulation velocity, gas and solids holdups in all reactor sections have been measured and experimental values were satisfactorily predicted using an appropriate three-phase model. The results of this study may beapplied to suggest the optimal design (in terms of hydrodynamic behaviour) of a batch/continuous three-phase ALR for high cell density fermentations.
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spelling Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systemsAirliftThree-phase flowHydrodynamic modelSolids distributionGas-liquid separatorScience & TechnologyThe hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yeast biomass at different loadings up to 21 % (v/v) were used in order to mimic the solid phase of conventional high cell density systems. The main hydrodynamic parameters – liquid circulation velocity, gas and solids holdups in all reactor sections have been measured and experimental values were satisfactorily predicted using an appropriate three-phase model. The results of this study may beapplied to suggest the optimal design (in terms of hydrodynamic behaviour) of a batch/continuous three-phase ALR for high cell density fermentations.On a mené une étude hydrodynamique d’un réacteur airlift triphasique ayant une zone de tête élargie. On a étudié les effets de la conception des séparateurs gaz-solide-liquide et de la section transversale entre la colonne montante et le déversoir avec différents diamètres et longueurs du tube d’aspiration. Des billes d’alginate de calcium avec de la biomasse de levure piégée à différents taux de charge jusqu’à des taux de charge de 21 % en volume ont été employées afin d’imiter la phase solide de systèmes à forte masse volumique de cellules. Les principaux paramètres hydrodynamiques – la vitesse de circulation du liquide, les rétentions de gaz et de solides – dans toutes les sections du réacteur ont été mesurés et les valeurs expérimentales sont prédites de manière satisfaisante à l’aide d’un modèle triphasique approprié. Les résultats de cette étude peuvent servir à éatblir la conception optimale (en termes de comportement hydrodynamique) d’un réacteur airlift triphasique discontinu/continu pour des fermentations à forte masse volumique de cellules.Marie Curie Fellowship of the European Community programme Improving Human Research Potential - MCFI-2001-01504.Canadian Society for Chemical Engineering (CSChE)Universidade do MinhoKlein, JaroslavVicente, A. A.Teixeira, J. A.2003-082003-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/1692eng“Canadian journal of chemical enginerring”. 81:3-4 (2003) 433-443.0008-4034info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T06:31:34Zoai:repositorium.sdum.uminho.pt:1822/1692Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:55:44.527156Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
title Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
spellingShingle Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
Klein, Jaroslav
Airlift
Three-phase flow
Hydrodynamic model
Solids distribution
Gas-liquid separator
Science & Technology
title_short Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
title_full Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
title_fullStr Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
title_full_unstemmed Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
title_sort Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
author Klein, Jaroslav
author_facet Klein, Jaroslav
Vicente, A. A.
Teixeira, J. A.
author_role author
author2 Vicente, A. A.
Teixeira, J. A.
author2_role author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Klein, Jaroslav
Vicente, A. A.
Teixeira, J. A.
dc.subject.por.fl_str_mv Airlift
Three-phase flow
Hydrodynamic model
Solids distribution
Gas-liquid separator
Science & Technology
topic Airlift
Three-phase flow
Hydrodynamic model
Solids distribution
Gas-liquid separator
Science & Technology
description The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yeast biomass at different loadings up to 21 % (v/v) were used in order to mimic the solid phase of conventional high cell density systems. The main hydrodynamic parameters – liquid circulation velocity, gas and solids holdups in all reactor sections have been measured and experimental values were satisfactorily predicted using an appropriate three-phase model. The results of this study may beapplied to suggest the optimal design (in terms of hydrodynamic behaviour) of a batch/continuous three-phase ALR for high cell density fermentations.
publishDate 2003
dc.date.none.fl_str_mv 2003-08
2003-08-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/1692
url http://hdl.handle.net/1822/1692
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv “Canadian journal of chemical enginerring”. 81:3-4 (2003) 433-443.
0008-4034
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Canadian Society for Chemical Engineering (CSChE)
publisher.none.fl_str_mv Canadian Society for Chemical Engineering (CSChE)
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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