Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal

Bibliographic Details
Main Author: Coentre, Ricardo
Publication Date: 2021
Other Authors: Fonseca, Alexandra, Mendes, Tiago, Rebelo, Ana, Fernandes, Elisabete, Levy, Pedro, Gois, Carlos, Figueira, Maria Luísa
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10451/49467
Summary: © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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spelling Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in PortugalDepressionFirst-episode psychosisSchizophreniaSuicidal behaviour© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.Background: Suicide is one of the main causes of excess of premature death in psychotic patients. Published studies found that suicide risk begins in ultra-high risk of psychosis and continues in early years of the disease. Previous studies identifying predictive and risk factors associated with suicidality in first-episode psychosis (FEP) are highly inconsistent. Also, there are relatively few longitudinal studies on suicidal behaviour in FEP. The aim of this study was to examine prevalence, evolution and predictors of suicidal behaviour at baseline and the 12-month follow-up in patients presenting with FEP. Methods: One hundred and eighteen patients presenting with FEP were recruited from two early psychosis units in Portugal. A comprehensive assessment examining socio-demographic and clinical characteristics was administered at baseline and the 12-month follow-up. Odds ratio were calculated using logistic regression analyses. McNemar test was used to evaluate the evolution of suicidal behaviour and depression prevalence from baseline to 12 months of follow-up. Results: Follow-up data were available for 60 participants from the 118 recruited. Approximately 25.4% of the patients had suicidal behaviour at the baseline evaluation, with a significant reduction during the follow-up period to 13.3% (p = 0.035). A multivariate binary logistic regression showed that a history of suicidal behaviour and depression at baseline independently predicted suicidal behaviour at baseline, and a history of suicidal behaviour and low levels of total cholesterol predicted suicidal behaviour at the 12-month follow-up. A significant proportion of patients also had depression at the baseline evaluation (43.3%), with the last month of suicidal behaviour at baseline independently predicting depression at this time. Conclusions: The findings of our study indicate that suicidal behaviour was prevalent on the year after FEP. Patients with a history of suicidal behaviour, depression at baseline and low levels of cholesterol should undergo close evaluation, monitoring and possible intervention in order to reduce suicide risk in the early phases of psychosis.Springer NatureRepositório da Universidade de LisboaCoentre, RicardoFonseca, AlexandraMendes, TiagoRebelo, AnaFernandes, ElisabeteLevy, PedroGois, CarlosFigueira, Maria Luísa2021-09-08T14:19:06Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49467engAnn Gen Psychiatry. 2021 Jul 6;20(1):3510.1186/s12991-021-00356-01744-859Xinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:36:56Zoai:repositorio.ulisboa.pt:10451/49467Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:17:04.230413Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
title Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
spellingShingle Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
Coentre, Ricardo
Depression
First-episode psychosis
Schizophrenia
Suicidal behaviour
title_short Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
title_full Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
title_fullStr Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
title_full_unstemmed Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
title_sort Suicidal behaviour after first-episode psychosis: results from a 1-year longitudinal study in Portugal
author Coentre, Ricardo
author_facet Coentre, Ricardo
Fonseca, Alexandra
Mendes, Tiago
Rebelo, Ana
Fernandes, Elisabete
Levy, Pedro
Gois, Carlos
Figueira, Maria Luísa
author_role author
author2 Fonseca, Alexandra
Mendes, Tiago
Rebelo, Ana
Fernandes, Elisabete
Levy, Pedro
Gois, Carlos
Figueira, Maria Luísa
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Coentre, Ricardo
Fonseca, Alexandra
Mendes, Tiago
Rebelo, Ana
Fernandes, Elisabete
Levy, Pedro
Gois, Carlos
Figueira, Maria Luísa
dc.subject.por.fl_str_mv Depression
First-episode psychosis
Schizophrenia
Suicidal behaviour
topic Depression
First-episode psychosis
Schizophrenia
Suicidal behaviour
description © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
publishDate 2021
dc.date.none.fl_str_mv 2021-09-08T14:19:06Z
2021
2021-01-01T00:00:00Z
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dc.relation.none.fl_str_mv Ann Gen Psychiatry. 2021 Jul 6;20(1):35
10.1186/s12991-021-00356-0
1744-859X
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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