A harmonized occupational biomonitoring approach
| Main Author: | |
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| Publication Date: | 2024 |
| Other Authors: | , , , , , , , , , , , , , , , , , , |
| Format: | Article |
| Language: | eng |
| Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Download full: | http://hdl.handle.net/10362/172762 |
Summary: | Publisher Copyright: © 2024 |
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A harmonized occupational biomonitoring approachBiological monitoringEffect biomarkersExposure biomarkersRisk assessmentRisk managementToxicokineticsEnvironmental Science(all)SDG 3 - Good Health and Well-beingPublisher Copyright: © 2024Biomonitoring has been widely used in assessing exposures in both occupational and public health complementing chemical risk assessments because it measures the concentrations of chemical substances in human body fluids (e.g., urine and blood). Biomonitoring considers all routes and sources of exposure. An occupational biomonitoring guidance document has been elaborated (OECD Occupational Biomonitoring Guidance) within the OECD framework and specifically, the Working Parties on Exposure and Hazard Assessment by scientific experts from 40 institutes and organizations representing 15 countries. The guidance provides practical information for assessing chemical exposures in occupational settings including the three common routes of exposure: inhalation, skin absorption and ingestion due to hand to mouth contact. The elaborated stepwise approach for conducting biomonitoring is tailored for occupational health professionals, scientists, risk assessors, and regulators. It includes methods for selecting appropriate biomarkers, devising sampling strategies, and assessing laboratories for validated analytical methods for the biomarker of interest, and ensuring timely feedback of results. Furthermore, it describes procedures for setting up efficient biomonitoring programs based on the Similar Exposure Group (SEG) approaches. Derived health-based human exposure biomarker assessment values called Occupational Biomonitoring Levels (OBLs) are proposed for use in occupational exposure and risk assessment. It also helps with the interpretation of biomonitoring results routinely collected and procedures for communicating biomonitoring results at individual, collective, and workplace levels. Ethical considerations associated with biomonitoring are also discussed. The ultimate goal of this biomonitoring approach is to promote harmonized application and interpretation of biomarkers as well as evidence-based occupational risk management measures.Comprehensive Health Research Centre (CHRC) - Pólo ENSPEscola Nacional de Saúde Pública (ENSP)Centro de Investigação em Saúde Pública (CISP/PHRC)RUNHopf, Nancy B.Rousselle, ChristophePoddalgoda, DevikaLamkarkach, FaridaBessems, JosSchmid, KasparJones, KateTakaki, KokiCasteleyn, LudwineZare Jeddi, MaryamBader, MichaelKoller, MichaelBrowne, PatienceFitzGerald, RexViegas, SusanaGöen, ThomasSantonen, TiinaVäänänen, VirpiDuca, Radu CorneliuPasanen-Kase, Robert2024-09-30T22:34:19Z2024-092024-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/172762eng0160-4120PURE: 100298695https://doi.org/10.1016/j.envint.2024.108990info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-10-07T01:39:37Zoai:run.unl.pt:10362/172762Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T18:55:21.539143Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
A harmonized occupational biomonitoring approach |
| title |
A harmonized occupational biomonitoring approach |
| spellingShingle |
A harmonized occupational biomonitoring approach Hopf, Nancy B. Biological monitoring Effect biomarkers Exposure biomarkers Risk assessment Risk management Toxicokinetics Environmental Science(all) SDG 3 - Good Health and Well-being |
| title_short |
A harmonized occupational biomonitoring approach |
| title_full |
A harmonized occupational biomonitoring approach |
| title_fullStr |
A harmonized occupational biomonitoring approach |
| title_full_unstemmed |
A harmonized occupational biomonitoring approach |
| title_sort |
A harmonized occupational biomonitoring approach |
| author |
Hopf, Nancy B. |
| author_facet |
Hopf, Nancy B. Rousselle, Christophe Poddalgoda, Devika Lamkarkach, Farida Bessems, Jos Schmid, Kaspar Jones, Kate Takaki, Koki Casteleyn, Ludwine Zare Jeddi, Maryam Bader, Michael Koller, Michael Browne, Patience FitzGerald, Rex Viegas, Susana Göen, Thomas Santonen, Tiina Väänänen, Virpi Duca, Radu Corneliu Pasanen-Kase, Robert |
| author_role |
author |
| author2 |
Rousselle, Christophe Poddalgoda, Devika Lamkarkach, Farida Bessems, Jos Schmid, Kaspar Jones, Kate Takaki, Koki Casteleyn, Ludwine Zare Jeddi, Maryam Bader, Michael Koller, Michael Browne, Patience FitzGerald, Rex Viegas, Susana Göen, Thomas Santonen, Tiina Väänänen, Virpi Duca, Radu Corneliu Pasanen-Kase, Robert |
| author2_role |
author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Comprehensive Health Research Centre (CHRC) - Pólo ENSP Escola Nacional de Saúde Pública (ENSP) Centro de Investigação em Saúde Pública (CISP/PHRC) RUN |
| dc.contributor.author.fl_str_mv |
Hopf, Nancy B. Rousselle, Christophe Poddalgoda, Devika Lamkarkach, Farida Bessems, Jos Schmid, Kaspar Jones, Kate Takaki, Koki Casteleyn, Ludwine Zare Jeddi, Maryam Bader, Michael Koller, Michael Browne, Patience FitzGerald, Rex Viegas, Susana Göen, Thomas Santonen, Tiina Väänänen, Virpi Duca, Radu Corneliu Pasanen-Kase, Robert |
| dc.subject.por.fl_str_mv |
Biological monitoring Effect biomarkers Exposure biomarkers Risk assessment Risk management Toxicokinetics Environmental Science(all) SDG 3 - Good Health and Well-being |
| topic |
Biological monitoring Effect biomarkers Exposure biomarkers Risk assessment Risk management Toxicokinetics Environmental Science(all) SDG 3 - Good Health and Well-being |
| description |
Publisher Copyright: © 2024 |
| publishDate |
2024 |
| dc.date.none.fl_str_mv |
2024-09-30T22:34:19Z 2024-09 2024-09-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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http://hdl.handle.net/10362/172762 |
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http://hdl.handle.net/10362/172762 |
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eng |
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eng |
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0160-4120 PURE: 100298695 https://doi.org/10.1016/j.envint.2024.108990 |
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