Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal

Bibliographic Details
Main Author: Manageiro, Vera
Publication Date: 2015
Other Authors: Ferreira, Eugénia, Almeida, Joana, Barbosa, Stephanie, Simões, Constança, Bonomo, Robert A., Caniça, Manuela
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.18/3720
Summary: Among the 2,105 Enterobacteriaceae tested in a survey done in Portugal, 165 were nonsusceptible to carbapenems, from which 35 (26 Klebsiella pneumoniae, 3 Escherichia coli, 2 Enterobacter aerogenes, and 3 Enterobacter cloacae isolates and 1 Klebsiella oxytoca isolate) were confirmed to be carbapenemase producers by the presence of 30 Tn4401d-blaKPC-3, 4 intI3-blaGES-5, and one intI1-blaVIM-2 gene, alone or in combination with other bla genes. The dissemination of blaKPC-3 gene carried by an IncF plasmid suggests lateral gene transfer as a major mechanism of dissemination.
id RCAP_b6e52ae82c4a8c88f81b14ea601791a9
oai_identifier_str oai:repositorio.insa.pt:10400.18/3720
network_acronym_str RCAP
network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository_id_str https://opendoar.ac.uk/repository/7160
spelling Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in PortugalResistência aos AntibióticosCarbapenemasesKPC-3PortugalEnterobacteriaceaeAmong the 2,105 Enterobacteriaceae tested in a survey done in Portugal, 165 were nonsusceptible to carbapenems, from which 35 (26 Klebsiella pneumoniae, 3 Escherichia coli, 2 Enterobacter aerogenes, and 3 Enterobacter cloacae isolates and 1 Klebsiella oxytoca isolate) were confirmed to be carbapenemase producers by the presence of 30 Tn4401d-blaKPC-3, 4 intI3-blaGES-5, and one intI1-blaVIM-2 gene, alone or in combination with other bla genes. The dissemination of blaKPC-3 gene carried by an IncF plasmid suggests lateral gene transfer as a major mechanism of dissemination.American Society for MicrobiologyRepositório Científico do Instituto Nacional de SaúdeManageiro, VeraFerreira, EugéniaAlmeida, JoanaBarbosa, StephanieSimões, ConstançaBonomo, Robert A.Caniça, Manuela2016-03-22T17:18:08Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/3720eng0066-480410.1128/AAC.05065-14info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-26T14:24:14Zoai:repositorio.insa.pt:10400.18/3720Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T21:39:08.052627Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
title Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
spellingShingle Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
Manageiro, Vera
Resistência aos Antibióticos
Carbapenemases
KPC-3
Portugal
Enterobacteriaceae
title_short Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
title_full Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
title_fullStr Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
title_full_unstemmed Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
title_sort Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
author Manageiro, Vera
author_facet Manageiro, Vera
Ferreira, Eugénia
Almeida, Joana
Barbosa, Stephanie
Simões, Constança
Bonomo, Robert A.
Caniça, Manuela
author_role author
author2 Ferreira, Eugénia
Almeida, Joana
Barbosa, Stephanie
Simões, Constança
Bonomo, Robert A.
Caniça, Manuela
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Manageiro, Vera
Ferreira, Eugénia
Almeida, Joana
Barbosa, Stephanie
Simões, Constança
Bonomo, Robert A.
Caniça, Manuela
dc.subject.por.fl_str_mv Resistência aos Antibióticos
Carbapenemases
KPC-3
Portugal
Enterobacteriaceae
topic Resistência aos Antibióticos
Carbapenemases
KPC-3
Portugal
Enterobacteriaceae
description Among the 2,105 Enterobacteriaceae tested in a survey done in Portugal, 165 were nonsusceptible to carbapenems, from which 35 (26 Klebsiella pneumoniae, 3 Escherichia coli, 2 Enterobacter aerogenes, and 3 Enterobacter cloacae isolates and 1 Klebsiella oxytoca isolate) were confirmed to be carbapenemase producers by the presence of 30 Tn4401d-blaKPC-3, 4 intI3-blaGES-5, and one intI1-blaVIM-2 gene, alone or in combination with other bla genes. The dissemination of blaKPC-3 gene carried by an IncF plasmid suggests lateral gene transfer as a major mechanism of dissemination.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2016-03-22T17:18:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/3720
url http://hdl.handle.net/10400.18/3720
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0066-4804
10.1128/AAC.05065-14
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833599365053153280

Similar Items