Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates

Bibliographic Details
Main Author: Shearn, Rylan
Publication Date: 2020
Other Authors: Wright, Alison E., Mousset, Sylvain, Régis, Corinne, Penel, Simon, Lemaitre, Jean-François, Douay, Guillaume, Crouau-Roy, Brigitte, Lecompte, Emilie, Marais, Gabriel A.B.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.5/20745
Summary: Short Report
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spelling Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primatesprimatessex chromosomespseudoautosomal boundaryShort ReportSex chromosomes are typically comprised of a non-recombining region and a recombining pseudoautosomal region. Accurately quantifying the relative size of these regions is critical for sex-chromosome biology both from a functional and evolutionary perspective. The evolution of the pseudoautosomal boundary (PAB) is well documented in haplorrhines (apes and monkeys) but not in strepsirrhines (lemurs and lorises). Here, we studied the PAB of seven species representing the main strepsirrhine lineages by sequencing a male and a female genome in each species and using sex differences in coverage to identify the PAB. We found that during primate evolution, the PAB has remained unchanged in strepsirrhines whereas several recombination suppression events moved the PAB and shortened the pseudoautosomal region in haplorrhines. Strepsirrhines are well known to have much lower sexual dimorphism than haplorrhines. We suggest that mutations with antagonistic effects between males and females have driven recombination suppression and PAB evolution in haplorrhineseLife Sciences PublicationsRepositório da Universidade de LisboaShearn, RylanWright, Alison E.Mousset, SylvainRégis, CorinnePenel, SimonLemaitre, Jean-FrançoisDouay, GuillaumeCrouau-Roy, BrigitteLecompte, EmilieMarais, Gabriel A.B.2021-01-05T15:52:48Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/20745engShearn et al. eLife 2020;9:e63650https://doi.org/10.7554/eLife.63650info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T16:11:48Zoai:repositorio.ulisboa.pt:10400.5/20745Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T04:05:20.608301Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
title Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
spellingShingle Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
Shearn, Rylan
primates
sex chromosomes
pseudoautosomal boundary
title_short Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
title_full Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
title_fullStr Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
title_full_unstemmed Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
title_sort Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
author Shearn, Rylan
author_facet Shearn, Rylan
Wright, Alison E.
Mousset, Sylvain
Régis, Corinne
Penel, Simon
Lemaitre, Jean-François
Douay, Guillaume
Crouau-Roy, Brigitte
Lecompte, Emilie
Marais, Gabriel A.B.
author_role author
author2 Wright, Alison E.
Mousset, Sylvain
Régis, Corinne
Penel, Simon
Lemaitre, Jean-François
Douay, Guillaume
Crouau-Roy, Brigitte
Lecompte, Emilie
Marais, Gabriel A.B.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Shearn, Rylan
Wright, Alison E.
Mousset, Sylvain
Régis, Corinne
Penel, Simon
Lemaitre, Jean-François
Douay, Guillaume
Crouau-Roy, Brigitte
Lecompte, Emilie
Marais, Gabriel A.B.
dc.subject.por.fl_str_mv primates
sex chromosomes
pseudoautosomal boundary
topic primates
sex chromosomes
pseudoautosomal boundary
description Short Report
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2021-01-05T15:52:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/20745
url http://hdl.handle.net/10400.5/20745
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Shearn et al. eLife 2020;9:e63650
https://doi.org/10.7554/eLife.63650
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv eLife Sciences Publications
publisher.none.fl_str_mv eLife Sciences Publications
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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