Solitary fibrous tumor of the kidney: a report of two cases

• Main Author: Oliveira, Rui Pedro Caetano M.
• Publication Date: 2019
• Other Authors: Silva, Edgar Miguel C. L. T., Marinho, Carol dos Anjos, Lopez, José Ignacio, Castro, Lígia Romana O. A. P.
• Format: Article
• Language: por
• Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
• Download full: https://hdl.handle.net/10316/107109; https://doi.org/10.5935/1676-2444.20190003
• topic: solitary fibrous tumors; kidney neoplasms; immunohistochemistry; tumor fibroso solitário pleural; neoplasias renais; imuno-histoquímica; tumor fibroso solitario pleural; neoplasias renales; inmunohistoquímica

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral mass; another with hilar lesion perceived following investigation of hematuria. Both revealed a spindle-cell proliferation, without mitosis and necrosis. Immunohistochemical studies: positivity for CD34, CD99 and B-cell lymphoma 2 (Bcl-2). No sign of disease were evident nine and five months after surgery, respectively. SFT is mostly benign, but can show malignant behavior. Morphologic and immunohistochemical characteristics are essential for diagnosis.