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Optimal time for constant drug infusion initialization in neuromuscular blockade control

Bibliographic Details
Main Author: Angela Miranda
Publication Date: 2014
Other Authors: Teresa Mendonca, Rocha, P
Format: Book
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://repositorio-aberto.up.pt/handle/10216/110088
Summary: This paper presents a control strategy for neuromuscular blockade (NMB) level, in order to determine the optimal time to initialize the administration of the muscle relaxant rocuronium by means of the continuous infusion of a constant dose. The constant value of muscle relaxant for a particular patient undergoing general anesthesia is computed in order to guarantee that the steady-state value of neuromuscular blockade level is the desired reference value. In order to apply this open-loop control strategy, the patient's NMB response to rocuronium is assumed to be modeled by a recently proposed parameter parsimonious model.
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spelling Optimal time for constant drug infusion initialization in neuromuscular blockade controlBiotecnologia ambientalEnvironmental biotechnologyThis paper presents a control strategy for neuromuscular blockade (NMB) level, in order to determine the optimal time to initialize the administration of the muscle relaxant rocuronium by means of the continuous infusion of a constant dose. The constant value of muscle relaxant for a particular patient undergoing general anesthesia is computed in order to guarantee that the steady-state value of neuromuscular blockade level is the desired reference value. In order to apply this open-loop control strategy, the patient's NMB response to rocuronium is assumed to be modeled by a recently proposed parameter parsimonious model.20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookapplication/pdfhttps://repositorio-aberto.up.pt/handle/10216/110088eng10.1109/memea.2014.6860068Angela MirandaTeresa MendoncaRocha, Pinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-27T18:25:27Zoai:repositorio-aberto.up.pt:10216/110088Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T22:48:05.706180Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Optimal time for constant drug infusion initialization in neuromuscular blockade control
title Optimal time for constant drug infusion initialization in neuromuscular blockade control
spellingShingle Optimal time for constant drug infusion initialization in neuromuscular blockade control
Angela Miranda
Biotecnologia ambiental
Environmental biotechnology
title_short Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_full Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_fullStr Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_full_unstemmed Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_sort Optimal time for constant drug infusion initialization in neuromuscular blockade control
author Angela Miranda
author_facet Angela Miranda
Teresa Mendonca
Rocha, P
author_role author
author2 Teresa Mendonca
Rocha, P
author2_role author
author
dc.contributor.author.fl_str_mv Angela Miranda
Teresa Mendonca
Rocha, P
dc.subject.por.fl_str_mv Biotecnologia ambiental
Environmental biotechnology
topic Biotecnologia ambiental
Environmental biotechnology
description This paper presents a control strategy for neuromuscular blockade (NMB) level, in order to determine the optimal time to initialize the administration of the muscle relaxant rocuronium by means of the continuous infusion of a constant dose. The constant value of muscle relaxant for a particular patient undergoing general anesthesia is computed in order to guarantee that the steady-state value of neuromuscular blockade level is the desired reference value. In order to apply this open-loop control strategy, the patient's NMB response to rocuronium is assumed to be modeled by a recently proposed parameter parsimonious model.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/book
format book
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://repositorio-aberto.up.pt/handle/10216/110088
url https://repositorio-aberto.up.pt/handle/10216/110088
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1109/memea.2014.6860068
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833599875489464320

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