The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?

Bibliographic Details
Main Author: Almeida, Cátia
Publication Date: 2023
Other Authors: Gonçalves-Nobre, J. Guilherme, Alpuim Costa, Diogo, Barata, Pedro
Format: Other
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/172755
Summary: Publisher Copyright: Copyright © 2023 Almeida, Gonçalves-Nobre, Alpuim Costa and Barata.
id RCAP_b22df1a0b63760eebe6202e6726f995e
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network_acronym_str RCAP
network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?atherosclerosiscardiovascular diseasesdysbiosisgut microbiotagut-heart axishypertensionSCFAsTMAOGastroenterologyHepatologySDG 3 - Good Health and Well-beingPublisher Copyright: Copyright © 2023 Almeida, Gonçalves-Nobre, Alpuim Costa and Barata.The gut-heart axis is an emerging concept highlighting the crucial link between gut microbiota and cardiovascular diseases (CVDs). Recent studies have demonstrated that gut microbiota is pivotal in regulating host metabolism, inflammation, and immune function, critical drivers of CVD pathophysiology. Despite a strong link between gut microbiota and CVDs, this ecosystem’s complexity still needs to be fully understood. The short-chain fatty acids, trimethylamine N-oxide, bile acids, and polyamines are directly or indirectly involved in the development and prognosis of CVDs. This review explores the relationship between gut microbiota metabolites and CVDs, focusing on atherosclerosis and hypertension, and analyzes personalized microbiota-based modulation interventions, such as physical activity, diet, probiotics, prebiotics, and fecal microbiota transplantation, as a promising strategy for CVD prevention and treatment.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNAlmeida, CátiaGonçalves-Nobre, J. GuilhermeAlpuim Costa, DiogoBarata, Pedro2024-09-30T22:33:19Z2023-102023-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/172755eng2813-1169PURE: 100267123https://doi.org/10.3389/fgstr.2023.1235126info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-11-11T01:38:46Zoai:run.unl.pt:10362/172755Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T18:55:21.158760Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
title The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
spellingShingle The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
Almeida, Cátia
atherosclerosis
cardiovascular diseases
dysbiosis
gut microbiota
gut-heart axis
hypertension
SCFAs
TMAO
Gastroenterology
Hepatology
SDG 3 - Good Health and Well-being
title_short The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
title_full The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
title_fullStr The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
title_full_unstemmed The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
title_sort The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?
author Almeida, Cátia
author_facet Almeida, Cátia
Gonçalves-Nobre, J. Guilherme
Alpuim Costa, Diogo
Barata, Pedro
author_role author
author2 Gonçalves-Nobre, J. Guilherme
Alpuim Costa, Diogo
Barata, Pedro
author2_role author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Almeida, Cátia
Gonçalves-Nobre, J. Guilherme
Alpuim Costa, Diogo
Barata, Pedro
dc.subject.por.fl_str_mv atherosclerosis
cardiovascular diseases
dysbiosis
gut microbiota
gut-heart axis
hypertension
SCFAs
TMAO
Gastroenterology
Hepatology
SDG 3 - Good Health and Well-being
topic atherosclerosis
cardiovascular diseases
dysbiosis
gut microbiota
gut-heart axis
hypertension
SCFAs
TMAO
Gastroenterology
Hepatology
SDG 3 - Good Health and Well-being
description Publisher Copyright: Copyright © 2023 Almeida, Gonçalves-Nobre, Alpuim Costa and Barata.
publishDate 2023
dc.date.none.fl_str_mv 2023-10
2023-10-01T00:00:00Z
2024-09-30T22:33:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/other
format other
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/172755
url http://hdl.handle.net/10362/172755
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2813-1169
PURE: 100267123
https://doi.org/10.3389/fgstr.2023.1235126
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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