Plastic antibody for the diagnosis of acute myocardial infarction
| Main Author: | |
|---|---|
| Publication Date: | 2024 |
| Other Authors: | , |
| Language: | eng |
| Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Download full: | http://hdl.handle.net/10400.22/26373 |
Summary: | (Introduction) Novel application Plastic Antibody that responds to a cardiac biomarker, myoglobin (Myo). Imprint stage with electropolymerization of ortho-phenylenediamine (OPD) in the presence of Myo. Template removal from polymeric matrix digested by trypsin. The films acted as biomimetic artificial antibodies and were fabricated on a screen-printed platinium (Pt) electrode (SPE) modified with electroactive Prussian blue nanocubes (PBNCs) to take a step towards disposable sensors for point-of-care applications. The devices showed linear responses to Myo in SWV assays up to 0.01 and 10000 ng/mL. |
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Plastic antibody for the diagnosis of acute myocardial infarctionPlastic antibodiesDiagnosisMyocardial infarction(Introduction) Novel application Plastic Antibody that responds to a cardiac biomarker, myoglobin (Myo). Imprint stage with electropolymerization of ortho-phenylenediamine (OPD) in the presence of Myo. Template removal from polymeric matrix digested by trypsin. The films acted as biomimetic artificial antibodies and were fabricated on a screen-printed platinium (Pt) electrode (SPE) modified with electroactive Prussian blue nanocubes (PBNCs) to take a step towards disposable sensors for point-of-care applications. The devices showed linear responses to Myo in SWV assays up to 0.01 and 10000 ng/mL.REPOSITÓRIO P.PORTORicardo, JacintaMartins, GabrielaMoreira, Felismina T.C.2024-11-08T15:42:50Z20242024-01-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/26373enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:19:49Zoai:recipp.ipp.pt:10400.22/26373Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:48:42.172877Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
Plastic antibody for the diagnosis of acute myocardial infarction |
| title |
Plastic antibody for the diagnosis of acute myocardial infarction |
| spellingShingle |
Plastic antibody for the diagnosis of acute myocardial infarction Ricardo, Jacinta Plastic antibodies Diagnosis Myocardial infarction |
| title_short |
Plastic antibody for the diagnosis of acute myocardial infarction |
| title_full |
Plastic antibody for the diagnosis of acute myocardial infarction |
| title_fullStr |
Plastic antibody for the diagnosis of acute myocardial infarction |
| title_full_unstemmed |
Plastic antibody for the diagnosis of acute myocardial infarction |
| title_sort |
Plastic antibody for the diagnosis of acute myocardial infarction |
| author |
Ricardo, Jacinta |
| author_facet |
Ricardo, Jacinta Martins, Gabriela Moreira, Felismina T.C. |
| author_role |
author |
| author2 |
Martins, Gabriela Moreira, Felismina T.C. |
| author2_role |
author author |
| dc.contributor.none.fl_str_mv |
REPOSITÓRIO P.PORTO |
| dc.contributor.author.fl_str_mv |
Ricardo, Jacinta Martins, Gabriela Moreira, Felismina T.C. |
| dc.subject.por.fl_str_mv |
Plastic antibodies Diagnosis Myocardial infarction |
| topic |
Plastic antibodies Diagnosis Myocardial infarction |
| description |
(Introduction) Novel application Plastic Antibody that responds to a cardiac biomarker, myoglobin (Myo). Imprint stage with electropolymerization of ortho-phenylenediamine (OPD) in the presence of Myo. Template removal from polymeric matrix digested by trypsin. The films acted as biomimetic artificial antibodies and were fabricated on a screen-printed platinium (Pt) electrode (SPE) modified with electroactive Prussian blue nanocubes (PBNCs) to take a step towards disposable sensors for point-of-care applications. The devices showed linear responses to Myo in SWV assays up to 0.01 and 10000 ng/mL. |
| publishDate |
2024 |
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2024-11-08T15:42:50Z 2024 2024-01-01T00:00:00Z |
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conference object |
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info:eu-repo/semantics/publishedVersion |
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http://hdl.handle.net/10400.22/26373 |
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http://hdl.handle.net/10400.22/26373 |
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eng |
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eng |
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