Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter

Bibliographic Details
Main Author: Gil, Solange
Publication Date: 2013
Other Authors: Leal, Rodolfo O., Duarte, Ana, McGahie, David, Sepúlveda, Nuno, Siborro, Inês, Cravo, Joana, Cartaxeiro, Clara, Tavares, Luís M.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.5/7210
Summary: Articles in International Journals
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spelling Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelterFeline immunodeficiency virusFeline Leukemia VirusInterferonTherapyShelterFeline herpesvirusFeline coronavirusFeline calicivirusArticles in International JournalsFeline Immnunodeficiency (FIV) and Feline Leukemia (FeLV) viruses are common infectious agents in stray cats and shelter environments. Recombinant feline interferon-x (rFeIFNx) has shown an antiviral action not only against FIV and FeLV but also against herpesvirus (FHV-1) and calicivirus (FCV). Sixteen naturally infected FIV/FeLV cats were followed during rFeIFNx therapy in order to monitor clinical signs and to correlate with excretion of concomitant viruses (FCV, FHV-1, feline coronavirus (FCoV) and parvovirus (FPV)). Cats were submitted to clinical evaluations and concomitant virus excretion assessement. Comparing D0–D65, 10/16 cats improved clinical scores. Of the 10 cats positive for FHV-1 on D0, 4 were negative and 6 reduced viral loads. Of the 11 FCoV positive cats, 9 reduced viral loads. The 13 FCV positive cats and the FPV positive cat were negative on D65. In conclusion, rFeIFNx improves clinical signs and reduces concurrent viral excretion in naturally infected retroviral cats.Elsevier Ltd.Repositório da Universidade de LisboaGil, SolangeLeal, Rodolfo O.Duarte, AnaMcGahie, DavidSepúlveda, NunoSiborro, InêsCravo, JoanaCartaxeiro, ClaraTavares, Luís M.2014-09-25T15:52:45Z2013-062013-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/7210engGil, S., et al. (2013). Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter. Research in Veterinary Science 94(3), 753–763. doi: 10.1016/j.rvsc.2012.09.0250034-528810.1016/j.rvsc.2012.09.025info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T15:23:47Zoai:repositorio.ulisboa.pt:10400.5/7210Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:41:56.144625Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
title Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
spellingShingle Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
Gil, Solange
Feline immunodeficiency virus
Feline Leukemia Virus
Interferon
Therapy
Shelter
Feline herpesvirus
Feline coronavirus
Feline calicivirus
title_short Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
title_full Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
title_fullStr Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
title_full_unstemmed Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
title_sort Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter
author Gil, Solange
author_facet Gil, Solange
Leal, Rodolfo O.
Duarte, Ana
McGahie, David
Sepúlveda, Nuno
Siborro, Inês
Cravo, Joana
Cartaxeiro, Clara
Tavares, Luís M.
author_role author
author2 Leal, Rodolfo O.
Duarte, Ana
McGahie, David
Sepúlveda, Nuno
Siborro, Inês
Cravo, Joana
Cartaxeiro, Clara
Tavares, Luís M.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Gil, Solange
Leal, Rodolfo O.
Duarte, Ana
McGahie, David
Sepúlveda, Nuno
Siborro, Inês
Cravo, Joana
Cartaxeiro, Clara
Tavares, Luís M.
dc.subject.por.fl_str_mv Feline immunodeficiency virus
Feline Leukemia Virus
Interferon
Therapy
Shelter
Feline herpesvirus
Feline coronavirus
Feline calicivirus
topic Feline immunodeficiency virus
Feline Leukemia Virus
Interferon
Therapy
Shelter
Feline herpesvirus
Feline coronavirus
Feline calicivirus
description Articles in International Journals
publishDate 2013
dc.date.none.fl_str_mv 2013-06
2013-06-01T00:00:00Z
2014-09-25T15:52:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/7210
url http://hdl.handle.net/10400.5/7210
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Gil, S., et al. (2013). Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter. Research in Veterinary Science 94(3), 753–763. doi: 10.1016/j.rvsc.2012.09.025
0034-5288
10.1016/j.rvsc.2012.09.025
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier Ltd.
publisher.none.fl_str_mv Elsevier Ltd.
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833601800993767424

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