Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms
| Main Author: | |
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| Publication Date: | 2017 |
| Other Authors: | , , , , , , |
| Language: | eng |
| Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Download full: | https://hdl.handle.net/1822/47178 |
Summary: | I Simpósio de Bioquímica Aplicada |
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Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilmsAntimicrobialHoneyE. coliBacteriophageBiofilmsI Simpósio de Bioquímica AplicadaWound colonization by biofilms-forming bacteria is one of the main obstacles to the treatment of chronic wounds, causing a number of biological and financial problems. Biofilms are structured communities of bacterial cells enclosed in a self-produced polymeric matrix, adhered to inert or living surfaces, blocking antibiotics and patients immune cells from reaching bacteria. Bacterio(phages), viruses infecting exclusively bacteria, and honey are being considered as valuable alternatives to treat a variety of infections (Table 1). Phages are harmless to mammalian cells, specific for target bacteria therefore not affecting commensal microflora, have the ability to selfreplicate as long as the host is present, and are effective against antibiotic resistant bacteria. Honey is a complex substance with broad spectrum antimicrobial activity, essentially attributed to the high sugar content, low pH, the presence of hydrogen peroxide and methylglyoxal that reacts with important biological molecules (RNA, DNA and proteins). Honey had yet the potential to promote tissue regeneration, cicatrization, decrease inflammation, improving wound healing. In this work the combination of those two antimicrobial agents was considered in the control E. coli biofilms.Hospital Escala Braga (Braga,Portugal) for providing the clinical isolate. This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope off the strategic funding of the UID/BIO/04469/2013 unit and COMPETE 2020(POCI-01-0145-FEDER-006684) and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte 2020-Programa Operacional Regional do Norte and the Project RECI/BBB-EBI/0179/2012(FCOMP-01-0124-FEDER-027462) and the project PTDC/CVT-EPI/4008/2014(POCI-01-0145-FEDER-016598). Portuguese Foundation for Science and Technology (FCT) through the SFRH/BPD/69356/2010 and SFRH/BD/93078/2013. FCT (IF/01413/2013)info:eu-repo/semantics/publishedVersionUniversidade do MinhoRibeiro, HenriqueOliveira, Ana Cristina AfonsoSilva, Ana Catarina Ramos LopesSilva, Maria DanielaRodrigues, Célia FortunaMelo, Luís Daniel RodriguesHenriques, Ana FilipaSillankorva, Sanna2017-052017-05-01T00:00:00Zconference posterinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/1822/47178engRibeiro, Henrique; Oliveira, A.; Silva, A.; Silva, Maria Daniela; Rodrigues, Célia F.; Melo, Luís D. R.; Henriques, Ana Filipa; Sillankorva, Sanna, Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms. I Simpósio de Bioquímica Aplicada. Braga, Portugal, 31 May, 652757, 2017.https://simposiobqaplicada.wixsite.com/sbqainfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-11-09T01:21:32Zoai:repositorium.sdum.uminho.pt:1822/47178Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T16:31:11.098186Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms |
| title |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms |
| spellingShingle |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms Ribeiro, Henrique Antimicrobial Honey E. coli Bacteriophage Biofilms |
| title_short |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms |
| title_full |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms |
| title_fullStr |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms |
| title_full_unstemmed |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms |
| title_sort |
Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms |
| author |
Ribeiro, Henrique |
| author_facet |
Ribeiro, Henrique Oliveira, Ana Cristina Afonso Silva, Ana Catarina Ramos Lopes Silva, Maria Daniela Rodrigues, Célia Fortuna Melo, Luís Daniel Rodrigues Henriques, Ana Filipa Sillankorva, Sanna |
| author_role |
author |
| author2 |
Oliveira, Ana Cristina Afonso Silva, Ana Catarina Ramos Lopes Silva, Maria Daniela Rodrigues, Célia Fortuna Melo, Luís Daniel Rodrigues Henriques, Ana Filipa Sillankorva, Sanna |
| author2_role |
author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade do Minho |
| dc.contributor.author.fl_str_mv |
Ribeiro, Henrique Oliveira, Ana Cristina Afonso Silva, Ana Catarina Ramos Lopes Silva, Maria Daniela Rodrigues, Célia Fortuna Melo, Luís Daniel Rodrigues Henriques, Ana Filipa Sillankorva, Sanna |
| dc.subject.por.fl_str_mv |
Antimicrobial Honey E. coli Bacteriophage Biofilms |
| topic |
Antimicrobial Honey E. coli Bacteriophage Biofilms |
| description |
I Simpósio de Bioquímica Aplicada |
| publishDate |
2017 |
| dc.date.none.fl_str_mv |
2017-05 2017-05-01T00:00:00Z |
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conference poster |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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publishedVersion |
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https://hdl.handle.net/1822/47178 |
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https://hdl.handle.net/1822/47178 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Ribeiro, Henrique; Oliveira, A.; Silva, A.; Silva, Maria Daniela; Rodrigues, Célia F.; Melo, Luís D. R.; Henriques, Ana Filipa; Sillankorva, Sanna, Synergistic antimicrobial interaction of honey and bacteriophage in Escherichia coli biofilms. I Simpósio de Bioquímica Aplicada. Braga, Portugal, 31 May, 652757, 2017. https://simposiobqaplicada.wixsite.com/sbqa |
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