The Role of Bone Biopsy in the Management of CKD-MBD

Bibliographic Details
Main Author: Ferreira, AC
Publication Date: 2021
Other Authors: Cohen-Solal, M, D’Haese, PC, Ferreira, A
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.17/4294
Summary: A bone biopsy is still considered the gold standard for diagnosis of renal osteodystrophy. It allows to measure both static and dynamic parameters of bone remodeling and is the only method able to evaluate mineralization and allows analysis of both cortical and trabecular bone. Although bone volume can be measured indirectly by dual-energy X-ray absorptiometry, mineralization defects, bone metal deposits, cellular number/activity, and even turnover abnormalities are difficult to determine by techniques other than qualitative bone histomorphometry. In this review, we evaluate the role of bone biopsy in the clinical practice.
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spelling The Role of Bone Biopsy in the Management of CKD-MBDBone histomorphometryBone histomorphometryRenal osteodystrophyHCC NEFA bone biopsy is still considered the gold standard for diagnosis of renal osteodystrophy. It allows to measure both static and dynamic parameters of bone remodeling and is the only method able to evaluate mineralization and allows analysis of both cortical and trabecular bone. Although bone volume can be measured indirectly by dual-energy X-ray absorptiometry, mineralization defects, bone metal deposits, cellular number/activity, and even turnover abnormalities are difficult to determine by techniques other than qualitative bone histomorphometry. In this review, we evaluate the role of bone biopsy in the clinical practice.SpringerlinkRepositório da Unidade Local de Saúde São JoséFerreira, ACCohen-Solal, MD’Haese, PCFerreira, A2022-12-06T12:49:35Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/4294eng10.1007/s00223-021-00838-zinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-06T16:51:08Zoai:repositorio.chlc.pt:10400.17/4294Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:21:50.703509Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv The Role of Bone Biopsy in the Management of CKD-MBD
title The Role of Bone Biopsy in the Management of CKD-MBD
spellingShingle The Role of Bone Biopsy in the Management of CKD-MBD
Ferreira, AC
Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
title_short The Role of Bone Biopsy in the Management of CKD-MBD
title_full The Role of Bone Biopsy in the Management of CKD-MBD
title_fullStr The Role of Bone Biopsy in the Management of CKD-MBD
title_full_unstemmed The Role of Bone Biopsy in the Management of CKD-MBD
title_sort The Role of Bone Biopsy in the Management of CKD-MBD
author Ferreira, AC
author_facet Ferreira, AC
Cohen-Solal, M
D’Haese, PC
Ferreira, A
author_role author
author2 Cohen-Solal, M
D’Haese, PC
Ferreira, A
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Unidade Local de Saúde São José
dc.contributor.author.fl_str_mv Ferreira, AC
Cohen-Solal, M
D’Haese, PC
Ferreira, A
dc.subject.por.fl_str_mv Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
topic Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
description A bone biopsy is still considered the gold standard for diagnosis of renal osteodystrophy. It allows to measure both static and dynamic parameters of bone remodeling and is the only method able to evaluate mineralization and allows analysis of both cortical and trabecular bone. Although bone volume can be measured indirectly by dual-energy X-ray absorptiometry, mineralization defects, bone metal deposits, cellular number/activity, and even turnover abnormalities are difficult to determine by techniques other than qualitative bone histomorphometry. In this review, we evaluate the role of bone biopsy in the clinical practice.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01T00:00:00Z
2022-12-06T12:49:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/4294
url http://hdl.handle.net/10400.17/4294
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1007/s00223-021-00838-z
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springerlink
publisher.none.fl_str_mv Springerlink
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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