Hyaluronic acid - Based wound dressings: A review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2020 |
| Outros Autores: | , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Texto Completo: | http://hdl.handle.net/10400.6/10286 |
Resumo: | Hyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of skin extracellular matrix (ECM) and it is involved in the inflammatory response, angiogenesis, and tissue regeneration process. Due to the intrinsic properties of HA (such as biocompatibility, biodegradability and hydrophilic character), it has been used to produce different wound dressings, namely sponges, films, hydrogels, and electrospun membranes. Herein, an overview of the different HA-based wound dressings that have been produced so far is provided as well as the future directions regarding the strategies aimed to improve the mechanical stability of HA-based wound dressings, along with the incorporation of biomolecules intended to ameliorate their biological performance during the healing process. |
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Hyaluronic acid - Based wound dressings: A reviewHyaluronic acidWound dressingWound healingHyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of skin extracellular matrix (ECM) and it is involved in the inflammatory response, angiogenesis, and tissue regeneration process. Due to the intrinsic properties of HA (such as biocompatibility, biodegradability and hydrophilic character), it has been used to produce different wound dressings, namely sponges, films, hydrogels, and electrospun membranes. Herein, an overview of the different HA-based wound dressings that have been produced so far is provided as well as the future directions regarding the strategies aimed to improve the mechanical stability of HA-based wound dressings, along with the incorporation of biomolecules intended to ameliorate their biological performance during the healing process.ElsevieruBibliorumGraça, Mariana F. P.Miguel, Sónia P.Cabral, Cátia S. D.Correia, I.J.2022-05-10T00:30:18Z2020-04-272020-04-27T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/10286eng10.1016/j.carbpol.2020.116364info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-11T14:42:54Zoai:ubibliorum.ubi.pt:10400.6/10286Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T01:20:18.101981Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
Hyaluronic acid - Based wound dressings: A review |
| title |
Hyaluronic acid - Based wound dressings: A review |
| spellingShingle |
Hyaluronic acid - Based wound dressings: A review Graça, Mariana F. P. Hyaluronic acid Wound dressing Wound healing |
| title_short |
Hyaluronic acid - Based wound dressings: A review |
| title_full |
Hyaluronic acid - Based wound dressings: A review |
| title_fullStr |
Hyaluronic acid - Based wound dressings: A review |
| title_full_unstemmed |
Hyaluronic acid - Based wound dressings: A review |
| title_sort |
Hyaluronic acid - Based wound dressings: A review |
| author |
Graça, Mariana F. P. |
| author_facet |
Graça, Mariana F. P. Miguel, Sónia P. Cabral, Cátia S. D. Correia, I.J. |
| author_role |
author |
| author2 |
Miguel, Sónia P. Cabral, Cátia S. D. Correia, I.J. |
| author2_role |
author author author |
| dc.contributor.none.fl_str_mv |
uBibliorum |
| dc.contributor.author.fl_str_mv |
Graça, Mariana F. P. Miguel, Sónia P. Cabral, Cátia S. D. Correia, I.J. |
| dc.subject.por.fl_str_mv |
Hyaluronic acid Wound dressing Wound healing |
| topic |
Hyaluronic acid Wound dressing Wound healing |
| description |
Hyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of skin extracellular matrix (ECM) and it is involved in the inflammatory response, angiogenesis, and tissue regeneration process. Due to the intrinsic properties of HA (such as biocompatibility, biodegradability and hydrophilic character), it has been used to produce different wound dressings, namely sponges, films, hydrogels, and electrospun membranes. Herein, an overview of the different HA-based wound dressings that have been produced so far is provided as well as the future directions regarding the strategies aimed to improve the mechanical stability of HA-based wound dressings, along with the incorporation of biomolecules intended to ameliorate their biological performance during the healing process. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020-04-27 2020-04-27T00:00:00Z 2022-05-10T00:30:18Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10400.6/10286 |
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http://hdl.handle.net/10400.6/10286 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1016/j.carbpol.2020.116364 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Elsevier |
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Elsevier |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia |
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