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Synthesis of 2,3,5-substituted pyrrole derivatives

Bibliographic Details
Main Author: Ferreira, Paula M. T.
Publication Date: 2002
Other Authors: Maia, Hernâni Lopes Silva, Monteiro, Luís S.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://hdl.handle.net/1822/72927
Summary: 2,3,5-Substituted pyrrole derivatives are prepared by treatment of 2,3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the beta-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tert-butyloxycarbonyl)-dehydroalanine methyl ester.
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spelling Synthesis of 2,3,5-substituted pyrrole derivativesDehydroalanineDihydrofuranPyrroleDehydroprolineScience & Technology2,3,5-Substituted pyrrole derivatives are prepared by treatment of 2,3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the beta-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tert-butyloxycarbonyl)-dehydroalanine methyl ester.- Fundação para a Ciência e a Tecnologia(POCTI/1999/QUI/32689)ElsevierUniversidade do MinhoFerreira, Paula M. T.Maia, Hernâni Lopes SilvaMonteiro, Luís S.2002-06-172002-06-17T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/72927eng0040-403910.1016/S0040-4039(02)00810-9https://www.sciencedirect.com/science/article/pii/S0040403902008109info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-04-12T04:15:10Zoai:repositorium.sdum.uminho.pt:1822/72927Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T14:57:52.503021Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Synthesis of 2,3,5-substituted pyrrole derivatives
title Synthesis of 2,3,5-substituted pyrrole derivatives
spellingShingle Synthesis of 2,3,5-substituted pyrrole derivatives
Ferreira, Paula M. T.
Dehydroalanine
Dihydrofuran
Pyrrole
Dehydroproline
Science & Technology
title_short Synthesis of 2,3,5-substituted pyrrole derivatives
title_full Synthesis of 2,3,5-substituted pyrrole derivatives
title_fullStr Synthesis of 2,3,5-substituted pyrrole derivatives
title_full_unstemmed Synthesis of 2,3,5-substituted pyrrole derivatives
title_sort Synthesis of 2,3,5-substituted pyrrole derivatives
author Ferreira, Paula M. T.
author_facet Ferreira, Paula M. T.
Maia, Hernâni Lopes Silva
Monteiro, Luís S.
author_role author
author2 Maia, Hernâni Lopes Silva
Monteiro, Luís S.
author2_role author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Ferreira, Paula M. T.
Maia, Hernâni Lopes Silva
Monteiro, Luís S.
dc.subject.por.fl_str_mv Dehydroalanine
Dihydrofuran
Pyrrole
Dehydroproline
Science & Technology
topic Dehydroalanine
Dihydrofuran
Pyrrole
Dehydroproline
Science & Technology
description 2,3,5-Substituted pyrrole derivatives are prepared by treatment of 2,3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the beta-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tert-butyloxycarbonyl)-dehydroalanine methyl ester.
publishDate 2002
dc.date.none.fl_str_mv 2002-06-17
2002-06-17T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/72927
url https://hdl.handle.net/1822/72927
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0040-4039
10.1016/S0040-4039(02)00810-9
https://www.sciencedirect.com/science/article/pii/S0040403902008109
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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