Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders

Bibliographic Details
Main Author: Cotovio, Gonçalo
Publication Date: 2023
Other Authors: Ventura, Fabiana, da Silva, Daniel Rodrigues, Pereira, Patrícia, Oliveira-Maia, AJ
Format: Other
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/157671
Summary: Funding Information: G.C. was funded by Fundação para a Ciência e Tecnologia (FCT; Portugal) through a PhD scholarship (SFRH/BD/130210/2017. G.C. and A.J.O.-M. were supported by grant PTDC/MED-NEU/31331/2017 from FCT. A.J.O.-M. was supported by grant PTDC/MEC-PSQ/30302/2017-IC&DT-LISBOA-01-0145-FEDER, funded by national funds from FCT and co-funded by FEDER, under the Partnership Agreement Lisboa 2020—Programa Operacional Regional de Lisboa, and by a Starting Grant from the European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (grant agreement no. 950357). A.J.O.-M. was also supported by the BOUNCE project (grant agreement no. 777167) and by the FAITH project (grant agreement no. 875358), both funded by the European Union’s Horizon 2020 Research and Innovation Programme. The content of this study is solely the responsibility of the authors and does not necessarily represent the official views of the Fundação para a Ciência e Tecnologia or the European Research Council. Publisher Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland.
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spelling Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disordersapprovalclearancepsychiatric disordersregulatory agenciestranscranial magnetic stimulationNeuroscience(all)Funding Information: G.C. was funded by Fundação para a Ciência e Tecnologia (FCT; Portugal) through a PhD scholarship (SFRH/BD/130210/2017. G.C. and A.J.O.-M. were supported by grant PTDC/MED-NEU/31331/2017 from FCT. A.J.O.-M. was supported by grant PTDC/MEC-PSQ/30302/2017-IC&DT-LISBOA-01-0145-FEDER, funded by national funds from FCT and co-funded by FEDER, under the Partnership Agreement Lisboa 2020—Programa Operacional Regional de Lisboa, and by a Starting Grant from the European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (grant agreement no. 950357). A.J.O.-M. was also supported by the BOUNCE project (grant agreement no. 777167) and by the FAITH project (grant agreement no. 875358), both funded by the European Union’s Horizon 2020 Research and Innovation Programme. The content of this study is solely the responsibility of the authors and does not necessarily represent the official views of the Fundação para a Ciência e Tecnologia or the European Research Council. Publisher Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland.Non-invasive brain stimulation techniques (NIBS) have been widely used in both clinical and research contexts in neuropsychiatry. They are safe and well-tolerated, making NIBS an interest-ing option for application in different settings. Transcranial magnetic stimulation (TMS) is one of these strategies. It uses electromagnetic pulses for focal modulate ion of neuronal activity in brain cortical regions. When pulses are applied repeatedly (repetitive transcranial magnetic stimulation—rTMS), they are thought to induce long-lasting neuroplastic effects, proposed to be a therapeutic mechanism for rTMS, with efficacy and safety initially demonstrated for treatment-resistant depression (TRD). Since then, many rTMS treatment protocols emerged for other difficult to treat psychiatric conditions. Moreover, multiple clinical studies, including large multi-center trials and several meta-analyses, have confirmed its clinical efficacy in different neuropsychiatric disorders, resulting in evidence-based guidelines and recommendations. Currently, rTMS is cleared by multiple regulatory agencies for the treatment of TRD, depression with comorbid anxiety disorders, obsessive compulsive disorder, and substance use disorders, such as smoking cessation. Importantly, current research supports the potential future use of rTMS for other psychiatric syndromes, including the negative symptoms of schizophrenia and post-traumatic stress disorder. More precise knowledge of formal indications for rTMS therapeutic use in psychiatry is critical to enhance clinical decision making in this area.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNCotovio, GonçaloVentura, Fabianada Silva, Daniel RodriguesPereira, PatríciaOliveira-Maia, AJ2023-09-12T22:14:03Z2023-072023-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/157671eng2076-3425PURE: 70041145https://doi.org/10.3390/brainsci13071029info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-05-26T01:40:54Zoai:run.unl.pt:10362/157671Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:44:54.387935Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
title Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
spellingShingle Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
Cotovio, Gonçalo
approval
clearance
psychiatric disorders
regulatory agencies
transcranial magnetic stimulation
Neuroscience(all)
title_short Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
title_full Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
title_fullStr Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
title_full_unstemmed Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
title_sort Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders
author Cotovio, Gonçalo
author_facet Cotovio, Gonçalo
Ventura, Fabiana
da Silva, Daniel Rodrigues
Pereira, Patrícia
Oliveira-Maia, AJ
author_role author
author2 Ventura, Fabiana
da Silva, Daniel Rodrigues
Pereira, Patrícia
Oliveira-Maia, AJ
author2_role author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Cotovio, Gonçalo
Ventura, Fabiana
da Silva, Daniel Rodrigues
Pereira, Patrícia
Oliveira-Maia, AJ
dc.subject.por.fl_str_mv approval
clearance
psychiatric disorders
regulatory agencies
transcranial magnetic stimulation
Neuroscience(all)
topic approval
clearance
psychiatric disorders
regulatory agencies
transcranial magnetic stimulation
Neuroscience(all)
description Funding Information: G.C. was funded by Fundação para a Ciência e Tecnologia (FCT; Portugal) through a PhD scholarship (SFRH/BD/130210/2017. G.C. and A.J.O.-M. were supported by grant PTDC/MED-NEU/31331/2017 from FCT. A.J.O.-M. was supported by grant PTDC/MEC-PSQ/30302/2017-IC&DT-LISBOA-01-0145-FEDER, funded by national funds from FCT and co-funded by FEDER, under the Partnership Agreement Lisboa 2020—Programa Operacional Regional de Lisboa, and by a Starting Grant from the European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (grant agreement no. 950357). A.J.O.-M. was also supported by the BOUNCE project (grant agreement no. 777167) and by the FAITH project (grant agreement no. 875358), both funded by the European Union’s Horizon 2020 Research and Innovation Programme. The content of this study is solely the responsibility of the authors and does not necessarily represent the official views of the Fundação para a Ciência e Tecnologia or the European Research Council. Publisher Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-12T22:14:03Z
2023-07
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