Apoptose e proliferação celular na endometriose: estado da arte

Bibliographic Details
Main Author: Subtil,Simone
Publication Date: 2016
Other Authors: Torgal,Isabel, Dias,Margarida
Format: Article
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302016000100006
Summary: Endometriosis is a disease characterized by the ectopy of endometrial glands and stroma, which can significantly compromise the quality of life in childbearing-age women. Its etiology remains uncertain since retrograde menstruation does not completely explain the endometriosis implant fixation process. Apoptosis and cellular proliferation, fundamental processes to endometrial tissue homeostasis, present changes in the endometrium of women who suffer from this disease, which may help to explain its pathogenesis. Hormonal treatment usually controls symptoms associated with this disease. Its effects include the interference with the regulation of apoptosis and cellular proliferation. The objective of this review is to highlight the main subcellular environment changes in endometriosis, referring to the factors that regulate apoptosis and cellular proliferation, and how all those factors evolve with the hormonal treatment.
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spelling Apoptose e proliferação celular na endometriose: estado da arteEndometriosisApoptosisBcl-2BaxCellular proliferationEndometriosis is a disease characterized by the ectopy of endometrial glands and stroma, which can significantly compromise the quality of life in childbearing-age women. Its etiology remains uncertain since retrograde menstruation does not completely explain the endometriosis implant fixation process. Apoptosis and cellular proliferation, fundamental processes to endometrial tissue homeostasis, present changes in the endometrium of women who suffer from this disease, which may help to explain its pathogenesis. Hormonal treatment usually controls symptoms associated with this disease. Its effects include the interference with the regulation of apoptosis and cellular proliferation. The objective of this review is to highlight the main subcellular environment changes in endometriosis, referring to the factors that regulate apoptosis and cellular proliferation, and how all those factors evolve with the hormonal treatment.Euromédice, Edições Médicas Lda.2016-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302016000100006Acta Obstétrica e Ginecológica Portuguesa v.10 n.1 2016reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302016000100006Subtil,SimoneTorgal,IsabelDias,Margaridainfo:eu-repo/semantics/openAccess2024-02-06T17:21:33Zoai:scielo:S1646-58302016000100006Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T13:09:01.890507Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Apoptose e proliferação celular na endometriose: estado da arte
title Apoptose e proliferação celular na endometriose: estado da arte
spellingShingle Apoptose e proliferação celular na endometriose: estado da arte
Subtil,Simone
Endometriosis
Apoptosis
Bcl-2
Bax
Cellular proliferation
title_short Apoptose e proliferação celular na endometriose: estado da arte
title_full Apoptose e proliferação celular na endometriose: estado da arte
title_fullStr Apoptose e proliferação celular na endometriose: estado da arte
title_full_unstemmed Apoptose e proliferação celular na endometriose: estado da arte
title_sort Apoptose e proliferação celular na endometriose: estado da arte
author Subtil,Simone
author_facet Subtil,Simone
Torgal,Isabel
Dias,Margarida
author_role author
author2 Torgal,Isabel
Dias,Margarida
author2_role author
author
dc.contributor.author.fl_str_mv Subtil,Simone
Torgal,Isabel
Dias,Margarida
dc.subject.por.fl_str_mv Endometriosis
Apoptosis
Bcl-2
Bax
Cellular proliferation
topic Endometriosis
Apoptosis
Bcl-2
Bax
Cellular proliferation
description Endometriosis is a disease characterized by the ectopy of endometrial glands and stroma, which can significantly compromise the quality of life in childbearing-age women. Its etiology remains uncertain since retrograde menstruation does not completely explain the endometriosis implant fixation process. Apoptosis and cellular proliferation, fundamental processes to endometrial tissue homeostasis, present changes in the endometrium of women who suffer from this disease, which may help to explain its pathogenesis. Hormonal treatment usually controls symptoms associated with this disease. Its effects include the interference with the regulation of apoptosis and cellular proliferation. The objective of this review is to highlight the main subcellular environment changes in endometriosis, referring to the factors that regulate apoptosis and cellular proliferation, and how all those factors evolve with the hormonal treatment.
publishDate 2016
dc.date.none.fl_str_mv 2016-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302016000100006
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302016000100006
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302016000100006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Euromédice, Edições Médicas Lda.
publisher.none.fl_str_mv Euromédice, Edições Médicas Lda.
dc.source.none.fl_str_mv Acta Obstétrica e Ginecológica Portuguesa v.10 n.1 2016
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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