Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years?
| Main Author: | |
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| Publication Date: | 2024 |
| Other Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | eng |
| Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Download full: | http://hdl.handle.net/10362/172833 |
Summary: | © The Author(s) 2024. Published by Oxford University Press on behalf of the British Society for Rheumatology. |
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Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years?Axial spondyloarthritischronic back painquality of lifework productivity© The Author(s) 2024. Published by Oxford University Press on behalf of the British Society for Rheumatology.OBJECTIVE: To compare health-related quality of life (HRQoL) and work productivity in axial spondyloarthritis (axSpA) and non-axSpA patients with chronic back pain of < 2 years (2 y). METHODS: Baseline and 2 y data of patients included in the SPondyloArthritis Caught Early cohort were analyzed. HRQoL was assessed by the physical (PCS) and mental component summary (MCS) scores of the 36-Item Short-Form Health Survey; and presenteeism, absenteeism, work productivity loss (WPL) and activity impairment (AI) by the Work Productivity and Activity Impairment questionnaire. Linear or zero-inflated negative binomial regression was conducted to compare 2 y outcomes between groups (axSpA and non-axSpA), adjusting for the baseline value, sex, age and use of nonsteroidal anti-inflammatory drugs. RESULTS: There were 265 axSpA and 108 non-axSpA patients: males 52% vs 26%, mean age 29 vs 31 years, respectively. At baseline, non-axSpA patients showed worse PCS (mean 28.6 axSpA vs 26.6 non-axSpA), presenteeism (31.1% vs 37.3%), absenteeism (8.2% vs 10.3%), WPL (34.7% vs 44.1%) and AI (39.6% vs 48.5%). MCS was not impaired in either group. After 2 y, PCS, presenteeism, WPL and AI significantly improved in both groups; absenteeism only in axSpA. In multivariable analysis, axSpA (vs non-axSpA) was associated with 22% less WPL (incidence rate ratio [95% CI]: 0.78 [0.62; 0.98]) and 18% less AI (0.82 [0.69; 0.97]). CONCLUSION: HRQoL and work productivity are more impaired in non-axSpA (vs axSpA) at baseline and still after 2 y. Although most outcomes improve in both groups, axSpA is associated with larger improvements in work productivity and activity impairment.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Comprehensive Health Research Centre (CHRC) - pólo NMSRUNda Silva, Ana BentoRamiro, SofiaBoel, Annevan Lunteren, MirandaMarques, Mary Lucyvan de Sande, MarleenFongen, CamillaExarchou, SofiaRamonda, Robertavan der Heijde, Désiréevan Gaalen, Floris2024-10-01T22:29:08Z2025-042025-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/172833eng1462-0332PURE: 100432906https://doi.org/10.1093/rheumatology/keae346info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-05-26T01:41:36Zoai:run.unl.pt:10362/172833Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T18:55:24.634949Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? |
| title |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? |
| spellingShingle |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? da Silva, Ana Bento Axial spondyloarthritis chronic back pain quality of life work productivity |
| title_short |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? |
| title_full |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? |
| title_fullStr |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? |
| title_full_unstemmed |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? |
| title_sort |
Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after two years? |
| author |
da Silva, Ana Bento |
| author_facet |
da Silva, Ana Bento Ramiro, Sofia Boel, Anne van Lunteren, Miranda Marques, Mary Lucy van de Sande, Marleen Fongen, Camilla Exarchou, Sofia Ramonda, Roberta van der Heijde, Désirée van Gaalen, Floris |
| author_role |
author |
| author2 |
Ramiro, Sofia Boel, Anne van Lunteren, Miranda Marques, Mary Lucy van de Sande, Marleen Fongen, Camilla Exarchou, Sofia Ramonda, Roberta van der Heijde, Désirée van Gaalen, Floris |
| author2_role |
author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Comprehensive Health Research Centre (CHRC) - pólo NMS RUN |
| dc.contributor.author.fl_str_mv |
da Silva, Ana Bento Ramiro, Sofia Boel, Anne van Lunteren, Miranda Marques, Mary Lucy van de Sande, Marleen Fongen, Camilla Exarchou, Sofia Ramonda, Roberta van der Heijde, Désirée van Gaalen, Floris |
| dc.subject.por.fl_str_mv |
Axial spondyloarthritis chronic back pain quality of life work productivity |
| topic |
Axial spondyloarthritis chronic back pain quality of life work productivity |
| description |
© The Author(s) 2024. Published by Oxford University Press on behalf of the British Society for Rheumatology. |
| publishDate |
2024 |
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2024-10-01T22:29:08Z 2025-04 2025-04-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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http://hdl.handle.net/10362/172833 |
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eng |
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eng |
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1462-0332 PURE: 100432906 https://doi.org/10.1093/rheumatology/keae346 |
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