Non-coding antisense transcripts: fine regulation of gene expression in cancer

Bibliographic Details
Main Author: Santos, Francisco
Publication Date: 2022
Other Authors: Capela, Ana Maria, Mateus, Francisca, Nóbrega-Pereira, Sandrina, Jesus, Bruno Bernardes de
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10773/43330
Summary: Natural antisense transcripts (NATs) are coding or non-coding RNA sequences transcribed on the opposite direction from the same genomic locus. NATs are widely distributed throughout the human genome and seem to play crucial roles in physiological and pathological processes, through newly described and targeted mechanisms. NATs represent the intricate complexity of the genome organization and constitute another layer of potential targets in disease. Here, we focus on the interesting and unique role of non-coding NATs in cancer, paying particular attention to those acting as miRNA sponges.
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spelling Non-coding antisense transcripts: fine regulation of gene expression in cancerLong non-coding RNAslncRNAsAntisense transcriptsceRNAsCancerNatural antisense transcripts (NATs) are coding or non-coding RNA sequences transcribed on the opposite direction from the same genomic locus. NATs are widely distributed throughout the human genome and seem to play crucial roles in physiological and pathological processes, through newly described and targeted mechanisms. NATs represent the intricate complexity of the genome organization and constitute another layer of potential targets in disease. Here, we focus on the interesting and unique role of non-coding NATs in cancer, paying particular attention to those acting as miRNA sponges.Elsevier2025-01-10T14:53:22Z2022-10-10T00:00:00Z2022-10-10info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/43330eng10.1016/j.csbj.2022.10.009Santos, FranciscoCapela, Ana MariaMateus, FranciscaNóbrega-Pereira, SandrinaJesus, Bruno Bernardes deinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-01-13T01:49:44Zoai:ria.ua.pt:10773/43330Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T19:39:18.071592Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Non-coding antisense transcripts: fine regulation of gene expression in cancer
title Non-coding antisense transcripts: fine regulation of gene expression in cancer
spellingShingle Non-coding antisense transcripts: fine regulation of gene expression in cancer
Santos, Francisco
Long non-coding RNAs
lncRNAs
Antisense transcripts
ceRNAs
Cancer
title_short Non-coding antisense transcripts: fine regulation of gene expression in cancer
title_full Non-coding antisense transcripts: fine regulation of gene expression in cancer
title_fullStr Non-coding antisense transcripts: fine regulation of gene expression in cancer
title_full_unstemmed Non-coding antisense transcripts: fine regulation of gene expression in cancer
title_sort Non-coding antisense transcripts: fine regulation of gene expression in cancer
author Santos, Francisco
author_facet Santos, Francisco
Capela, Ana Maria
Mateus, Francisca
Nóbrega-Pereira, Sandrina
Jesus, Bruno Bernardes de
author_role author
author2 Capela, Ana Maria
Mateus, Francisca
Nóbrega-Pereira, Sandrina
Jesus, Bruno Bernardes de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos, Francisco
Capela, Ana Maria
Mateus, Francisca
Nóbrega-Pereira, Sandrina
Jesus, Bruno Bernardes de
dc.subject.por.fl_str_mv Long non-coding RNAs
lncRNAs
Antisense transcripts
ceRNAs
Cancer
topic Long non-coding RNAs
lncRNAs
Antisense transcripts
ceRNAs
Cancer
description Natural antisense transcripts (NATs) are coding or non-coding RNA sequences transcribed on the opposite direction from the same genomic locus. NATs are widely distributed throughout the human genome and seem to play crucial roles in physiological and pathological processes, through newly described and targeted mechanisms. NATs represent the intricate complexity of the genome organization and constitute another layer of potential targets in disease. Here, we focus on the interesting and unique role of non-coding NATs in cancer, paying particular attention to those acting as miRNA sponges.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-10T00:00:00Z
2022-10-10
2025-01-10T14:53:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/43330
url http://hdl.handle.net/10773/43330
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.csbj.2022.10.009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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