Synthesis of Unsymmetrical Methylenebisphenol Derivatives

Bibliographic Details
Main Author: Guieu, Samuel
Publication Date: 2013
Other Authors: Rocha, Joao, Silva, Artur M. S.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10773/19435
Summary: A simple and efficient route towards unsymmetrical methylenebisphenol derivatives is reported. This straightforward strategy avoids the use of harmful or dangerous chemicals, allowing the synthesis of highly functionalized bisphenyls with no need of protecting groups. The alkylation of the phenyl ring is selective for the para position of the hydroxyl substituent. All methylenebisphenols were obtained in a completely regioselective manner and isolated in high yields.
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spelling Synthesis of Unsymmetrical Methylenebisphenol DerivativesPTP1B INHIBITORSA simple and efficient route towards unsymmetrical methylenebisphenol derivatives is reported. This straightforward strategy avoids the use of harmful or dangerous chemicals, allowing the synthesis of highly functionalized bisphenyls with no need of protecting groups. The alkylation of the phenyl ring is selective for the para position of the hydroxyl substituent. All methylenebisphenols were obtained in a completely regioselective manner and isolated in high yields.GEORG THIEME VERLAG KG2017-12-07T19:12:41Z2013-01-01T00:00:00Z2013info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/19435eng0936-521410.1055/s-0032-1318394Guieu, SamuelRocha, JoaoSilva, Artur M. S.info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-06T04:06:01Zoai:ria.ua.pt:10773/19435Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T13:57:25.882028Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Synthesis of Unsymmetrical Methylenebisphenol Derivatives
title Synthesis of Unsymmetrical Methylenebisphenol Derivatives
spellingShingle Synthesis of Unsymmetrical Methylenebisphenol Derivatives
Guieu, Samuel
PTP1B INHIBITORS
title_short Synthesis of Unsymmetrical Methylenebisphenol Derivatives
title_full Synthesis of Unsymmetrical Methylenebisphenol Derivatives
title_fullStr Synthesis of Unsymmetrical Methylenebisphenol Derivatives
title_full_unstemmed Synthesis of Unsymmetrical Methylenebisphenol Derivatives
title_sort Synthesis of Unsymmetrical Methylenebisphenol Derivatives
author Guieu, Samuel
author_facet Guieu, Samuel
Rocha, Joao
Silva, Artur M. S.
author_role author
author2 Rocha, Joao
Silva, Artur M. S.
author2_role author
author
dc.contributor.author.fl_str_mv Guieu, Samuel
Rocha, Joao
Silva, Artur M. S.
dc.subject.por.fl_str_mv PTP1B INHIBITORS
topic PTP1B INHIBITORS
description A simple and efficient route towards unsymmetrical methylenebisphenol derivatives is reported. This straightforward strategy avoids the use of harmful or dangerous chemicals, allowing the synthesis of highly functionalized bisphenyls with no need of protecting groups. The alkylation of the phenyl ring is selective for the para position of the hydroxyl substituent. All methylenebisphenols were obtained in a completely regioselective manner and isolated in high yields.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01T00:00:00Z
2013
2017-12-07T19:12:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/19435
url http://hdl.handle.net/10773/19435
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0936-5214
10.1055/s-0032-1318394
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv GEORG THIEME VERLAG KG
publisher.none.fl_str_mv GEORG THIEME VERLAG KG
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833594203885535232

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